PubMed Health⌕ Search

Biomedical subjects

C G Morran

Publications and source records attributed to C G Morran.

22 records · Page 2Linked to original sources

Transcutaneous electrical stimulation for postoperative pain.

A prospective randomised trial was conducted to assess transcutaneous electrical stimulation in the management of postoperative pain and its effect on postoperative pulmonary function and respiratory complications. Consecutive patients undergoing abdominal surgery were allocated to receive transcutaneous electrical stimulation or 'sham' therapy. There was no significant difference in the amount of postoperative pain as measured by linear analogue pain scales or morphine requirements. Arterial oxygen and carbon dioxide tensions were similar in both groups. There was no difference in the incidence of postoperative chest infection. These results do not support the use of transcutaneous electrical stimulation following abdominal surgery.

Adult↗

Wound sepsis after low risk elective cholecystectomy: the effect of cefuroxime.

A prospective randomized double-blind study was performed to assess the value of a single intravenous injection of 1.5 g cefuroxime in the prevention of wound sepsis after low risk elective cholecystectomy. Wound infection developed in 10 of 81 control patients compared with 2 of 79 treated patients (P less than 0.05). Wound sepsis occurred more commonly in patients with infected bile or with a positive culture from a closing wound swab. Cefuroxime significantly reduced the isolation of staphylococci but not other organisms from the closing wound swab and also produced a significant reduction in wound infection in patients with sterile bile.

Cefuroxime↗

Comparison of morphine and sublingual buprenorphine following abdominal surgery.

In a prospective study, patients undergoing abdominal surgery were allocated randomly to receive intermittent morphine 10 mg i.m. (n = 41) or a single injection of buprenorphine 0.3 mg i.m. followed by sublingual buprenorphine 0.4 mg every 6 h (n = 39) for 3 days following operation. Patients receiving buprenorphine were allowed additional morphine, if required. Pain scores (linear analogue scale) in those patients receiving regular sublingual buprenorphine were consistently less than in those receiving intermittent morphine i.m. Half the patients receiving buprenorphine required no additional analgesia; only 15% required additional analgesia after the first day following operation. Arterial blood-gas analyses showed significant hypoxaemia and significantly greater carbon dioxide tensions in those receiving buprenorphine. These results suggest that a regimen based on the use of sublingual buprenorphine provides pain relief comparable to that provided by intermittent opiates i.m.

Abdomen↗

Randomized controlled trial of physiotherapy for postoperative pulmonary complications.

A prospective randomized controlled trial was conducted in patients undergoing elective cholecystectomy to assess the value of routine chest physiotherapy. One hundred and two patients entered the study: 47 patients developed no pulmonary complications, 29 had pulmonary atelectasis and a further 26 developed chest infection. The pattern of changes in arterial oxygen tension in the period after operation supported the clinical allocation of the patients. Of 51 patients not receiving physiotherapy, 11 developed atelectasis and 19 chest infection. Of 51 treated patients, 18 developed atelectasis and seven chest infection. Routine prophylactic postoperative chest physiotherapy decreased significantly the frequency of chest infection (P less than 0.02).

Adult↗