Synthesis and crystal and molecular structure of a 1,11-methano-steroid, 3-methoxy-1'beta-methyl-1,11alpha-methano-9beta-estra-1,3,5(10)-trien-17beta-ol.
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Biomedical subjects
Publications and source records attributed to C G Pitt.
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The 11-hydroxy metabolites of Delta(8).- and Delta(9)-tetrahydrocannabinol are more active than the parent compounds when administered to mice by either the intravenous or intracerebral route. Both Delta(8)- and Delta(9)-tetrahydrocannabinol are rapidly and extensively metabolized by the liver and not by the brain. The hypothesis that the 11-hydroxy metabolites may be the active form of tetrahydrocannabinol is discussed
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