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Biomedical subjects

C G Shaw

Publications and source records attributed to C G Shaw.

21 records · Page 2Linked to original sources

Computerized fluoroscopy techniques for intravenous study of cardiac chamber dynamics.

A computerized fluoroscopy system which was recently developed in our laboratories permits image contrast increases of 8-16 relative to conventional image intensifer fluoroscopy and permits study of canine and human ventricular wall motion using peripheral intravenous injections. Two time-dependent image subtraction algorithms are illustrated in connection with observation of artificially infarcted dog hearts. The first algorithm produces a display analogous to direct ventriculography using catheterization. The second displays regions of dyskinetic motion as anomalous image grey shades.

Animals↗

Three-beam K-edge imaging of iodine using differences between fluoroscopic video images: experimental results.

In an earlier article we discussed the rationale for using differences between video images in three-beam selective iodine K-edge imaging. Rather than combining three initial images Li linearly to yield the final image k1L1 + k2L2 + k3L3, differences between the Li were first generated and then combined either to linear or quadratic order. This approach was motivated by the desire to suppress the large multiplicative biases of fluoroscopic imaging and justified by theoretically proving that k1 + k2 + k3 is approximately equal to 0. In this paper we discuss the instrumentation and experimental results obtained from this difference-based technique. A specially-constructed apparatus is described which automatically selects the optimum combination coefficients and combines the difference images up to quadratic order at realtime video rates. Three methods for generating K-edge subtraction images are compared: the former approach in which the Li are linearly combined and combination of differences to linear and quadratic order. In imaging phantoms in which the iodine distribution is known, the resultant subtraction images from all three methods appear similar. Inspection of signal sizes shows that the quadratic difference-based approach provides superior bone and tissue residual suppression by about a factor of 2. In imaging phantoms in which the iodine distribution is unknown, incomplete suppression of x-ray scatter and image intensifier veiling glare prevent a quantitative comparison of performance of the three algorithms. An experiment verification is provided of the theorem which states that k1 + k2 + k3 is approximately equal to 0.

Fluoroscopy↗

Effects of scattered radiation and veiling glare in dual-energy tissue-bone imaging: a theoretical analysis.

Dual-energy subtraction imaging allows tissue and bone structures to be separated from each other and attenuating thicknesses measured. Potential applications include chest imaging, bone mineral measurement, angiography, and mammography. However, intrinsic to most x-ray detectors is the acceptance of scattered radiation as part of the image signal. Added to that is the veiling glare component when an image intensifier is used. Together, they result in erroneous transmission measurement and degrade the accuracy of energy subtraction processing. In this paper, the effects of scattered radiation and veiling glare on energy subtraction images are examined theoretically. A model is derived and used to compute the effects on the thickness signals, image contrast, and image noise as a function of the scatter glare to primary ratios. The ratios were measured on a point-by-point basis for a Rando chest phantom. For 96% of the image field studied, the thickness signals may be subject to an error ranging from 0 to -22.5 cm for tissue and 0 to 5.2 cm for bone. The image contrast in the tissue image may be reduced by a factor ranging from 1 to 59. The percentage of the uncanceled bone signals ranges from -52% to 52%. The contrast-to-noise ratio may be reduced by a factor ranging from 1 to 18.

Bone and Bones↗