Biomedical subjects

C Gürkan Zorlu

Publications and source records attributed to C Gürkan Zorlu.

3 recordsLinked to original sources

PubMed1996

Leiomyosarcoma of the vagina.

Vaginal leiomyoma is uncommon and borderline leiomyoma of the vagina is an extreme rarity. Leiomyoma of the vagina may undergo malignant change to become borderline malignancy or leiomyosarcoma. A 38-year-old woman, complaining of foul vaginal discharge and dyspareunia with 2 months duration, underwent total excision of tumor. The removed tumor was diagnosed as borderline case of leiomyoma histologically. Unfortunately, she had tumor recurrence within 4 months. Thus, it was more likely that the primary diagnosis was incorrect and that the diagnosis leiomyosarcoma has been missed. She underwent total abdominal hysterectomy, bilateral salphingo-oophorectomy and total vaginectomy. The final diagnosis was leiomyosarcoma. Three months later tumor recurred again and re-excision followed by chemotherapy was performed. However, she died of her disease on her 5th month following three courses of chemotherapy.

Adult↗

PubMed1996

Plasma human chorionic gonadotropin levels after induced abortion.

In the present study, we evaluated the elimination time and the disappearance curve of maternal plasma hCG after induced abortion in 44 patients. The patients were divided into two groups: patients in group 1 had gestations at or at less than 8 weeks and group 2 consisted of patients with gestations at more than 8 weeks in whom sharp curettage was utilized. The entire group had a mean of 48,342 mIU/ml baseline level of maternal plasma hCG. After the evacuation of the uterine cavity, a rapid decrease of plasma hCG occurred within the first week, followed by a gradual decline until elimination was total. The mean disappearance time of plasma hCG was 30 days. The disappearance curve of hCG was found to be in a form similar to that described before. No significant difference was found between the two groups. We conclude that when the appropriate method is used for pregnancy termination, the time between the procedure and disappearance of hCG depends on the initial hCG value.

Abortion, Induced↗

PubMed1996

Causative factors in first trimester abortion failure.

OBJECTIVE: To evaluate the main contributors to failed first trimester abortions. PATIENTS AND DESIGN: Forty-two cases of unintentional continued pregnancy were detected among 23,000 termination procedures performed between 1989 and 1995. The patients were diagnosed either at follow-up visits or at the time of operation due to abnormal pelvic findings or discrepancy between the expected and obtained tissue. RESULTS: The failure rate was found to be 0.18%. Among the patients with failed abortion 8 patients had unsuspected anomalies; two of these patients conceived with an intrauterine device in position; 7 patients had uterine malposition (2 markedly anteverted and 5 markedly retroverted), and 2 patients had leiomyomas. No genital disorder was identified in the remaining 25 women. Among these 25 women, 10 had gestations beyond 8 weeks, for which suction curettage followed by sharp curettage was performed. Among the remaining 15 in whom only suction curettage was used for termination, 13 had less than 6 weeks of gestation at the time of pregnancy termination. CONCLUSION: When a termination fails, when scanty tissue is obtained, or when doubt exists about the termination, an extrauterine pregnancy must be ruled out and other causes of termination failure should be considered such as technical failure, uterine anomaly, or malposition.

Abortion, Induced↗