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C Gander

Publications and source records attributed to C Gander.

3 recordsLinked to original sources

[Variability of phenomenology of epileptic crises in the newborn infant].

Epileptic seizures are more common in the newborn period than at any other time of life. If ictal behaviors accompany ictal EEG discharges, there is no particular problem. However, the most pressing controversy is whether neonatal seizures should be diagnosed on the basis of behavioral or EEG criteria. The proportion of seizures that are subclinical is much higher during the neonatal period than at any other time of life. Therefore the frequent occurrence in an intensive care unit of both subclinical seizures and suspicious stereotyped behaviors renders EEG of critical importance in the diagnosis of neonatal seizures. The authors discuss the large field of clinical and EEG phenomenology of neonatal seizures after twenty years of experience with EEG in neonatology.

Electroencephalography

Early diagnosis and evolution of deafness in childhood bacterial meningitis: a study using brainstem auditory evoked potentials.

Fifty-one children with bacterial meningitis were studied prospectively using serial recordings of brainstem auditory evoked potential (BAEP) from the earliest phase of the disease, according to a standardized protocol. The objectives were to make an early diagnosis and follow the evolution of deafness in the course of meningitis and evaluate the prognostic value of BAEP. Thirty-five children (68.6%) always had normal recordings; 11 children (21.6%) had transient BAEP abnormalities (prolonged wave V latency or elevated threshold for wave I), and five children (9.8%) had persistent pathologic BAEP recordings from the first examination at 48 hours until discharge from the hospital and have a persistent deafness. All recordings that were normal or pathologic at discharge were confirmed by behavioral audiometry 3 months later. These results show the early occurrence of deafness in the course of meningitis with a crucial phase of possible recovery or worsening occurring during the first 2 weeks. There were no cases of "late" deafness or "late" recovery (there was sometimes slight improvement) occurring after discharge; thus BAEPs have a prognostic value. However, observation of a child with clinically proven selective high-frequency postmeningitic deficit but without a hearing handicap, a disorder that was diagnosed early with BAEP (which tests only the high frequencies), is a warning that this method alone is insufficient and that clinical auditory surveillance and conventional audiometry remain necessary.

Adolescent