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Biomedical subjects

C Garabedian

Publications and source records attributed to C Garabedian.

7 recordsLinked to original sources

Acute arsenic ingestion.

A 21-year-old man presented in shock after ingesting 2 g of arsenic trioxide. He died within 37 hours despite intensive treatment that included intramuscular dimercaprol and hemodialysis. Hemodynamic and laboratory data are presented illustrating the multisystem toxicities of inorganic arsenic. Hemodialysis, previously described as an effective therapeutic adjunct, was shown to be ineffective in this case.

Acute Kidney Injury↗

Immunologic tolerance to heterologous immunoglobulin: its relation to in vitro filtration by macrophages.

The cellular and molecular basis for the difference in ability of BCG to induce tolerance in BALB/c and DBA/2 mice has been examined by in vitro biofiltration. It was found that incubation with the adherent cells from BALB/c but not DBA/2 spleens could remove the material from BGG which inhibited tolerance induction in BALB/c mice. This material was shown to represent only a trace component in BGG, was present in only certain commercial batches of BGG, and was apparently unrelated to the presence of aggregates or endotoxin.

Animals↗

Competency-based orientation for clinical nurse educators.

The orientation process highlights entry into new roles and responsibilities. The attainment of competence in this process can be enhanced through the appropriate identification of requisite knowledge and skills and the use of creative tools to establish an organized process and documentation of progress. Clinical educators in acute care settings require an orientation program that incorporates both clinical and educational components. Formal communication between a new hire and preceptor and subsequent documentation for both administrative and peer review provide increased accountability. Therefore, a variety of strategies, often melding the clinical and teaching roles, becomes crucial to a successful orientation program.

Competency-Based Education↗