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Biomedical subjects

C Gausi

Publications and source records attributed to C Gausi.

At least 19 recordsLinked to original sources

[Thrombosis and thrombocytopenia associated with the use of unfractionated heparin in a female patient with unstable angina].

A case of heparin-induced platelet activation with thrombocytopenia and several arterial emboli in a 60-year-old woman suffering unstable angina is presented. The early recognition of the syndrome, with cessation of heparin and the use of unfractionated heparin, led to an immediate remission of the thrombocytopenia and thromboembolic complications.

Angina, Unstable

[Thyroid dysfunction induced by amiodarone in Catalonia. Prevalence and characteristics].

The purpose of this study was to review the epidemiological aspects and the characteristics of the thyroid disfunction produced by amiodarone in Catalonia, an area with type I endemic goiter. For this purpose, three groups of patients have been studied: 1) 102 patients with prolonged amiodarone treatment, out of whom 6 (5.9%) presented hyperthyroidism, and 2 (1.9%) hypothyroidism. 2) 909 patients with hyperthyroidism of any origin out of which 42 (4.6%) were produced by amiodarone. 3) 203 patients presenting primary hypothyroidism of any origin out of which 11 (3.8%) were induced by amiodarone. Out of the 48 patients with amiodarone induced hyperthyroidism, 16 presented multinodular goiter, 2 toxic thyroid goiter and 7 Graves Basedow disease. Thyroid uptake of 131I was studied in 10 cases being normal or increased in six of them, all with a underlaying thyroid pathology. Out of the 13 patients with amiodarone induced hypothyroidism, 3 presented diffuse goiter; thyroid uptake of 131I was studied in 5 patients, being normal or increased in 4 cases, 2 of which with thyroid pathology. Amiodarone administration very often produces thyroid disfunction, specially hyperthyroidism. These patients with hyperfunctional thyroids usually present underlying thyroid pathologies in which thyroid uptake of 131I are frequently not suppressed as well as in those patients in whide amiodarone induced hypothyroidism.

Adolescent

Idiopathic hypertrophic subaortic stenosis and Wolff-Parkinson-White syndrome. Changes of obstruction in left ventricular outflow depending on the type of ventricular activation.

A case of idiopathic hypertrophic subaortic stenosis (IHSS) associated with Wolff-Parkinson-White (WPW) syndrome is studied. On three occasions preexcitation was suppressed with an intravenous injection of ajmaline. The left ventricular outflow tract obstruction (LVOTO) was analyzed; when WPW syndrome activation disappeared, the obstruction decreased. The ventricular depolarization pathway is noteworthy as a factor in the severity of LVOTO in IHSS.

Ajmaline