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Biomedical subjects

C Gheorghiu

Publications and source records attributed to C Gheorghiu.

At least 19 recordsLinked to original sources

Pineal vasotocin: release into cat cerebrospinal fluid by melanocyte-stimulating hormone release-inhibiting factor.

The intracarotid injection of both synthetic melanocyte-stimulating hormone release-inhibiting factor (MIF) and purified MIF prepared from bovine hypothalami induces arginine vasotocin release into cerebrospinal fluid of cats and significantly decreases the pineal arginine vasotocin content at 5 minutes after the injection. The present results demonstrate an extrapituitary endocrine effect of synthetic and purified bovine MIF.

Animals

Reversal by vasotocin of pinealectomy and constant light effects on the pituitary melanocyte-stimulating hormone (MSH) content in the mouse.

A single injection of 1 pg synthetic arginine vasotocin (AVT) into the third ventricle of the mouse completely prevented the pituitary MSH increase which occurs seven days after pinealectomy or 24 h after exposure to constant light. The same concentration of AVT injected into the third ventricle of normal mice markedly decreased the pituitary MSH content at 20 min following the injection. The present results suggest that AVT injected into the third ventricle of the mouse inhibits synthesis and/or release of MSH-release inhibiting factor (MIF).

Animals

[Hepatic tuberculosis].

Hepatic tuberculosis is well-known anatomicopathologically, consequent to necropsy and liver biopsy puncture, but the clinical aspect when the signs of the pulmonary localization are not dominant, may be similar to other "masked" affections, hepatic or extrahepatic, more often chronic hepatitis, hepatic tumours or prolonged febrile syndrome with many etiologic possibilities. The past history of the patients is very important as it confirms the observation of the histopathologic and possibly bacteriological examinations of a liver fragment. Three cases presumptively clinically diagnosed are presented and histopathologically verified for confirmation of the facts illustrated.

Adult