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Biomedical subjects

C Giovannini

Publications and source records attributed to C Giovannini.

At least 73 records · Page 4Linked to original sources
PubMed1982

[The influence, in normal subjects, of a high-protein normocaloric diet on the response of cortisol, ACTH, GH, and PRL to insulin hypoglycemia].

A protein rich diet causes a remarkable increment of plasma cortisol, corticotropin and somatotropin concentration, but does not modify the plasma prolactin level; this diet, moreover, is followed by a more vivacious response to the Lysin-8-Vasopressin test. In 10 healthy voluntary subjects we have studied the hormonal behaviour during the insulin-induced hypoglycemia test in course of equilibrated diet and after 15 days of protein-rich diet. In these two experimental conditions the insulin-induced hypoglycemia test has promoted a similar increment of the four hormones. The different behaviour between the two tests -Lysin-8-Vasopressin and insulin-induced hypoglycemia- indicates that the increased hormonal levels which follow a protein-rich diet are not provoked by a generic stress effect, but by a direct stimulation of the hypothalamo-hypophyseal structures.

Adolescent↗
PubMed1981

[Influence, in normal subjects, of an isocaloric hyperprotein diet on cortisol, ACTH, GH and PRL response to lysine-8-vasopressin].

The Lysin-8-Vasopressin test has been experimented in ten healthy subjects during normocaloric balanced diet and after hyperproteic-normocaloric diet. The levels of ACTH, Cortisol and GH are significantly more elevated after hyperproteic-normocaloric diet than in basal conditions. The levels of Prolactin do not show any remarkable change. These results can indicate the increased reactivity of the diencephalon-hypophysis-adrenal axis and of the hormones connected with the mechanisms of homeostasis and stress, probably correlated to more disposable proteic material and to the metabolic effects which follow.

Adrenocorticotropic Hormone↗
PubMed1981

[Behavior of basal values and circadian rhythm of ACTH, cortisol, PRL and GH in a high-protein diet].

Basal values and circadian rhythm of cortisol, ACTH, GH and PRL were studied in 8 normal subjects during a normal balanced caloric diet and during a high protein diet ( + 12% proteins ). GH, ACTH and cortisol levels were considerably higher following the protein rich diet probably on account of the metabolic processes directly related to the higher protein load.

Adrenocorticotropic Hormone↗
PubMed1980

[Critical analysis of the 2-hour test in mass screenings for the early detection of diabetes].

Out of 500 random trial subjects, taken for a mass-screening for early detection of diabetes mellitus, the Authors tried a correlation between the reliability of the "two-hour test" and the 2 h OGTT. The latter method provides more reliable results, allowing us to diagnose a high percentage of cases which is not possible if the simple two-hour test were used. Research of glycosuria in the course of OGTT did not show any real reliability, whereas it did prove useful in the preliminary phase of our research in order to distinguish the subjects for whom a deeper investigation would be advisable.

Diabetes Mellitus↗
PubMed1979

[Behavior of plasma cortisol during testing with insulin and with LVP in obese subjects compared to normal subjects after resperine administration].

The behaviour of plasma cortisol levels was studied in fifteen overweight subjects with comparison to normal subjects. In eight subjects the insulin hypoglycemic test was performed before and after medication with reserpine (4mg/24HR); the other seven subjects were tested with LVP before and after treatment with reserpine. In both cases, premedication with reserpine significantly reduce the cortisolemic response. This behaviour is similar to the response observed in normal subjects.

Humans↗
PubMed1979

[Influence of haloperidol on blood cortisol response to lysine-8-vasopressin in normal subjects].

The investigations were done on ten normal subjects. The LVP test was performed before and after intravenous-infusion of Haloperidol (Img). The results show that haloperidol eliminates the cortisolemic response during stimulation with LVP; that is most likely, in relation to the specific blocking effect of this drug on dopaminergic receptors in the hypothalamus and on the hypothalamo-diencephalic pathways.

Haloperidol↗