Biomedical subjects

C Goffin

Publications and source records attributed to C Goffin.

24 records · Page 2Linked to original sources

PubMed1983

Interstrand DNA crosslinks due to AP (apurinic/apyrimidinic) sites.

Storage of a solution of DNA containing apurinic sites, even at 4 degrees C leads to the appearance of interstrand crosslinks. Possible biological consequences of these crosslinks, when they appear in cell DNA, are briefly discussed. Formation of interstrand crosslinks in DNA containing tritium-labelled thymine and kept in an aqueous solution might be due, at least partly, to the loss of bases by the autoirradiated DNA.

Apurinic Acid↗

PubMed1982

Excision of apurinic sites from DNA with enzymes isolated from rat-liver chromatin.

Apurinic sites were excised from phi X174 RF DNA with two enzymes isolated from rat liver chromatin: an apurinic/apyrimidinic endodeoxyribonuclease and a 5'-3'-exonuclease; the resulting gap was filled with DNA polymerase beta also prepared from rat liver chromatin and the repair was fully terminated with T4 ligase.

Animals↗

PubMed1981

Localization of the phosphoester bond hydrolyzed by the major apurinic/apyrmidinic endodeoxyribonuclease from rat-liver chromatin.

The major apurinic/apyrimidinic (AP) endodeoxyribonuclease from rat liver chromatin, an enzyme specific for AP sites in DNA, cleaves the phosphodiester bridge which is the immediate neighbour of the AP site on its 5' side leaving 3'-hydroxyl and 5'-phosphate ends. In contrast with Escherichia coli endonuclease VI, this chromatin enzyme is inactive on reduced AP sites.

Animals↗

PubMed1974

User's guide to some new tests for hepatitis-B antigen.

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Adult↗

PubMedDate not supplied

Digital embolus arising from a pseudoaneurysm after radial artery catheterization: a case report.

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Aneurysm, False↗

PubMedDate not supplied

[Rupture of an abdominal aortic aneurysm in a nonagenarian].

Rupture of an infrarenal aortic aneurysm occurring in a 94- year old man is reported. Eight months after surgery the patient is still alive. Indications of elective surgery for asymptomatic abdominal aneurysm in the elderly are discussed.

Aged↗