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Biomedical subjects

C Goho

Publications and source records attributed to C Goho.

17 recordsLinked to original sources
PubMed1994

Hypothalamic hamartoma in oral-facial-digital syndrome type VI (Váradi syndrome).

Oral-facial-digital syndrome (OFDS) type VI (Váradi syndrome) is an autosomal recessive trait of orofacial anomalies, cerebellar dysgenesis, and polysyndactyly. Developmental anomalies of the posterior fossa, including cerebellar hypoplasia and variants of the Dandy-Walker complex, are the most common central nervous system malformations reported in patients with this syndrome. We report hypothalamic hamartoma, supernumerary maxillary incisor, and precocious puberty in a boy with OFDS type VI. We propose that hypothalamic hamartoma is an occasional manifestation of OFDS type VI.

Genes, Recessive↗
PubMed1992

Enhancement of antimicrobial properties of cavity varnish: a preliminary report.

Bacterial contamination beneath amalgam restorations has been a problem in restorative dentistry. Cavity varnish improves the marginal seal but possesses no antibacterial properties, and chlorhexidine gluconate is a known antimicrobial substance. This study investigated the efficacy of a chlorhexidine gluconate/cavity varnish mixture against Streptococcus mutans, S. salivarius, and Escherichia coli. The in vitro results indicated that the addition of chlorhexidine gluconate to cavity varnish improved its antimicrobial properties.

Bacteria↗
PubMedDate not supplied

Association between primary dentition wear and clinical temporomandibular dysfunction signs.

Dental wear facets often are considered indicators of temporomandibular dysfunction (TMD). Dental wear facets are common in children, but their association with TMD signs is unknown. A reproducible, clinical evaluation of TMD signs for young children shows no statistically significant association between primary dentition wear facets and clinical signs of TMD (P less than or equal to 0.05). Wear facets in young children do not appear to warrant TMD evaluation or treatment.

Chi-Square Distribution↗
PubMedDate not supplied

Ingestion of dental mirror fragments: report of case.

A case is reported in which one treated pediatric patient gave his plastic, disposable dental mirror to a 2.5-year-old sibling, who while playing chewed on the mirror and the mirrored glass surface broke in the child's mouth. After thorough examination including x-rays, the patient was released with no further complications. Potentially severe injuries could have occurred, resulting in legal liabilities.

Child, Preschool↗
PubMedDate not supplied

Chemoradiation therapy: effect on dental development.

Chemoradiation therapy used on pediatric oncology patients often causes dental developmental anomalies that affect future dental care. Defects noted include tooth and root agenesis, root thinning and shortening, and localized enamel defects. Histologically, these defects appear as osteoid-like niches in the developing dentin which alter the overlying enamel. Odontogenic cell sensitivity is dependent upon the position on the cell cycle and the mitotic activity at the time of chemoradiation therapy. Knowledge of the stage of dental development at the time of oncology treatment and the type of therapy allows the clinician to predict dental effects of the chemoradiation. Representative cases illustrate the clinical manifestations of chemoradiation on the developing dentition.

Ameloblasts↗
PubMedDate not supplied

Neonatal sublingual traumatic ulceration (Riga-Fede disease): reports of cases.

Neonatal sublingual traumatic ulcerations (Riga-Fede disease) can present as mild to severe ulcerations. The associated pain can interfere with infant nursing and nutrition. The preferred, conservative treatment consists of smoothing rough incisal edges, or placing round smooth composites over the incisal edges. Acute ulcerations, and a need for definite, rapid healing, may require extraction of the neonatal teeth.

Female↗