PubMed Health⌕ Search

Biomedical subjects

C Goodfellow

Publications and source records attributed to C Goodfellow.

4 recordsLinked to original sources
PubMed1998

System integration: a necessity.

Healthcare organizations are undergoing tremendous change in an attempt to become more flexible and adaptive. To be successful in any such transformation, organizations must build processes and systems that allow them to move with change and create a culture that allows individuals to thrive amid change. The authors describe how a community teaching hospital has attempted this through its partnership in a vertically integrated delivery system, its reorganization to product line management, its adoption of a shared governance structure, and its commitment to building a culture with strong relationships. Many of these processes and systems are in their infancy, but an examination of the journey will inform other organizations as they respond to change.

Delivery of Health Care, Integrated↗
PubMed1996

Pharmacological modulation of eosinophil influx into the lungs of Brown Norway rats.

A model of lung inflammation was developed in Brown Norway rats. Intense lung eosinophilia was induced by a single intravenous injection of Sephadex G-200 particles. The eosinophilia observed was preceded by an increase in cysteinyl leukotrienes found in lung lavage fluids. Theophylline and albuterol were tested in the model and found to be inactive, while dexamethasone was effective. Zileuton, a specific leukotriene inhibitor, was found to effectively inhibit leukotriene formation and the influx of eosinophils into the lungs of these Sephadex-treated animals. Studies with specific leukotriene D4 antagonists of the cysLT1 type receptor indicate that this leukotriene receptor is probably not involved directly in the eosinophilic inflammation. This model appears to be useful in characterizing potential anti-inflammatory effects of inhibitors by evaluating their ability to prevent eosinophil influx into the lung.

Animals↗
PubMed1981

Discrimination of the age of adolescent females on the basis of facial cues.

In an ongoing study of adolescent maternal-infant interaction, we investigated the accuracy with which judges could assign the age of two groups of females, based on videotaped facial cues alone. The two groups were eight "adolescents," whose ages were less than or equal to 17 years, and 20 "adults," whose ages were greater than 20 years. Twenty-seven judges, whose average age was 28.7 years with a range from 27 through 44 years of age, were asked to judge the ages of the subjects in the two groups. Overall, the judges were successful in identifying adolescents 41.8% of the time. There was no relationship between the ages of the judges and the accuracy of their judgments. On the basis of facial cues alone, our results clearly suggest that the process of assigning an individual to an adolescent or adult group is essentially random, approaching a 50/50 breakdown. This study supports the concept that observed differences between adolescents and adults interacting with their infants is due to actual differences in behavior and not the cultural bias of the judge.

Adolescent↗