PubMed Health⌕ Search

Biomedical subjects

C Graff

Publications and source records attributed to C Graff.

At least 19 recordsLinked to original sources
PubMed1992

The gene for Best's macular dystrophy is located at 11q13 in a Swedish family.

A large Swedish family with more than 250 cases of Best's macular dystrophy has been clinically and genetically studied. The gene was traced to a couple born in central Sweden in the 17th century. Highly significant evidence for genetic linkage to DNA markers on chromosome 11q13 was detected. A lod score of 15.12 was obtained at recombination fraction 0.01 with DNA marker INT2 (also called FGF3). The retinally expressed gene ROM1, which maps to the same chromosomal region is a candidate for this genetic disease.

Chromosomes, Human, Pair 11↗
PubMed1987

Recording electrophysiological signals from small moving animals: electrode fixation and low torque swivel for recording a weakly electric fish in a group.

A silicone rubber ring maintains an electrode on the electric organ of a mormyrid fish. The electrode is connected with a novel swivel, which allows free motion of the wire around its axis. The principle of the rotating contact is based on magnetic contact between a steel pin (moving) and a steel ball (fixed). Using this apparatus, a single fish within a group is recorded. The general electric activity of the group is recorded by means of two sets of fixed differential electrodes. These devices may be adapted for neuroethological studies of other small animals.

Animals↗