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Biomedical subjects

C Gutt

Publications and source records attributed to C Gutt.

22 records · Page 2Linked to original sources
PubMed1991

Experimental laparoscopic cholecystotomy.

This instrument set for a single puncture technique of laparoscopic cholecystotomy was developed in 100 phantom tests with pig gallbladders and was later evaluated in 12 animal experiments. No complications were observed. After clinical development, treatment on an outpatient basis under local anaesthesia seems possible. For the patient this would mean avoiding general anaesthesia, shorter hospitalization, pain reduction and good cosmetic results, while reducing expenditure for the public health authorities at the same time. To avoid recurrent stones, diet and low-dose drug therapy should be considered. Because the procedure is minimally invasive, repetition of the laparoscopic procedure seems justified if stones recur.

Animals↗
PubMedDate not supplied

Laparoscopic surgery in the rat. Description of a new technique.

We report a method of laparoscopic surgery in the rat. Our technique is illustrated by gastric fundoplication requiring two-handed dissection, suturing, and knot tying. This model for laparoscopic surgery is relatively inexpensive, can be extended to other operations, and makes use of an extensively studied animal. These factors may facilitate investigation of the physiologic effects of minimal access surgery.

Animals↗
PubMedDate not supplied

A prospective, randomised comparison of single- vs. multiple-dose antibiotic prophylaxis in penetrating trauma.

UNLABELLED: This study was designed to compare the clinical efficacy of a single dose of ceftriaxone with cefoxitin given 3 times a day for 3 days. METHODS: Patients had to have a penetrating injury to only one part of the body, reach the hospital within 2 h and be operated on within 16 h after the trauma. Patients were excluded if it appeared likely that they would require mechanical ventilation for more than 24 h. The same applies to open or grade II/III craniocerebral trauma. The end point was the occurrence of infections within 10 days. The costs of antibiotic treatment were also calculated. RESULTS: 96% of the ceftriaxone patients (n = 97) and 95% of the cefoxitin group (n = 98) remained infection-free. In neither treatment group was deep infection, abscess, phlegmon or sepsis seen. No additional surgery or intensive care due to infection was required. At $41.83 vs. $172.16, the average total cost of delivering antibiotic treatment was significantly lower in the ceftriaxone group (p < 0.001). CONCLUSION: Prophylaxis in penetrating trauma with a single dose of ceftriaxone is safe and has considerable practical and economic advantages.

Abdominal Injuries↗