Ascending aortic aneurysm causing pulmonary stenosis.
Explore the source record for details and available documents.
Adult↗
Biomedical subjects
C H Anyanwu
Publications and source records attributed to C H Anyanwu.
Aortic homograft valve replacement for postendocarditis aortic incompetence in early childhood. A case report.
A case of postendocarditis aortic incompetence with congenital ventricular septal defect in a 21-month-old child, treated successfully by homograft aortic valve replacement and closure of the ventricular septal defect, is reported. It appears that no similar case has previously been reported in the UK.
Aortic Valve↗
Congenital absence of left pericardium associated with sinus venosus atrial septal defect. (Report of a case and review).
Explore the source record for details and available documents.
Child↗
Miliary tuberculosis following homograft valve replacement.
Postoperative septicaemia with infective endocarditis is a recognized complication of open-heart surgery, in particular homograft or prosthetic replacement of cardiac valves. Several infective organisms, both bacterial and fungal, have been incriminated but infection due to tubercle bacilli has not, to our knowledge, been reported. The clinicopathological features of this condition are discussed. During a five-year period, over 800 homograft replacements in the aortic and/or mitral positions have been performed at Harefield Hospital. Seven cases of miliary tuberculosis following homograft valve replacement are descrbied here. In three, there was a past history suggestive of tuberculosis infections but necropsy failed to reveal any caseous or other tuberculous lesion apart from recent miliary tuberculosis. Vegetations on the homograft valves contained microcolonies of acid-fast bacilli in most cases. Tubercle bacilli of the human type were recovered by culture or guinea-pig inoculation in six of the seven cases, and in three the diagnosis was established during life; two of these survived on antituberculosis chemotherapy. The onset of symptoms varied from a few weeks to 12 months after operation. The main presenting symptom was intermittent pyrexia. In two patients the diagnosis was made on radiological and clinical grounds and in both, tubercle bacilli were grown from drill biopsy specimens of lung tissue. The source of infection was presumed to be the homograft valves contaminated in the postmorten room. The antibiotic mixture used in the sterilization of the homografts was not effective against tubercle bacilli.
Adult↗
Mitral incompetence and ventricular septal defects following non-penetrating injury.
A case of mitral incompetence and multiple ventricular septal defects following a non-penetrating chest injury is described. Cardiac injury was detected by electrocardiogram and by the appearance of a heart murmur in the second week after trauma. Superimposition of bacterial endocarditis seven years later caused cardiac decompensation and necessitated successful surgical treatment. Previous reported cases are reviewed.
Adult↗
Impacted esophageal foreign bodies of dental origin.
The use of dentures is becoming common even among Africans. So also is the problem of swallowed and impacted dentures. Their radiolucence makes radiological localization almost impossible, and because of their rigidity, large size, irregular and unyielding edges, impacted dentures are apt to produce lacerations during endoscopic removal from gullets rendered friable by impaction. Three patients with impacted radiolucent dentures are described in order to illustrate the problems of removal. It is suggested that the safest most effective method of removing impacted dentures in the esophagus is through an elective open esophagotomy.
Adult↗
A clinical evaluation of clavulanate-potentiated amoxycillin in the management of moderate to severe respiratory tract infections.
This study investigated the effects of clavulanate-potentiated amoxycillin in the management of moderate to severe respiratory tract infections. A total of 34 patients aged 10-70 years were studied to establish the clinical and bacterial efficacy of treatment and screened for unwanted effects and abnormal laboratory findings. Clavulanate-potentiated amoxycillin was given in dosages of 375 or 750 mg twice daily, orally, for a mean of 13 days (range 3-30 days). Patients were assessed at the end of 2 weeks and again on discharge from hospital (if later) for up to 6 months. Overall diminution in the number of symptoms was recorded at the end of the study; 78% of symptoms had disappeared after 2 weeks. The treatment proved highly effective in controlling respiratory tract infections in 94% of patients. The necessity for multiple drug therapy and parenteral administration was also avoided.
Adult↗
Clinical aspects of pulmonary and pleural carcinoma in Nigeria.
Carcinoma of the lung may not be uncommon in Nigeria and other parts of tropical Africa. Twenty-seven cases of pulmonary and pleural carcinoma seen at UNTH Enugu, are reviewed; 20 were primary and 7 were secondary. The 20 patients with primary carcinoma were aged 35-75 years (mean 51.8 years); there were 14 males and 6 females. Cigarette smoking was the possible aetiological factor in 10 cases while exposure to asbestos products was elicited in a case of mesothelioma. Massive pleura effusion was present in 60% of cases. Different histological cell types were represented but squamous cell and adenocarcinoma were predominating. Resection could be achieved in only 3 cases. Mean survival period was 103.5 days for the primary carcinoma, and 80.8 days for the secondary carcinomas. With increasing industrialisation, atmospheric pollution and cigarette smoking in Nigeria, the incidence and problems of bronchopulmonary carcinoma would be expected to rise.
Adolescent↗