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Biomedical subjects

C H Boren

Publications and source records attributed to C H Boren.

5 recordsLinked to original sources
PubMed1980

Profundapopliteal collateral index. A guide to successful profundaplasty.

The response to profundaplasty was evaluated in 232 limbs (163 patients) and correlated with segmental pressures and operative flow measurements. Of 150 limbs operated on for rest pain or ischemic necrosis, an inflow procedure (aortofemoral, femorofemoral, etc) combined with profundaplasty was successful in achieving limb salvage in 80 of 96 limbs (83%), but after profundaplasty alone only 26 of 54 limbs (48%) were salvaged. Using segmental pressure measurements, an index of the resistance of the profundapopliteal collateral system (PPCI) was calculated from the segmental pressure decrease across the knee, and demonstrated an inverse correlation with circulatory improvement. When profundaplasty was performed alone, successful limb salvage was associated with a mean PPCI of .18, compared with .46 in the group with unsatisfactory results. The PPCI is an accurate predictor of the hemodynamic potential of the geniculate collaterals and is useful in the selection of patients for profunda repair.

Blood Pressure↗
PubMed1980

Alkaline reflux gastritis: a reevaluation.

The results of Roux-Y reconstruction in 46 patients diagnosed as having alkaline reflux gastritis were analyzed to determine which factors in the preoperative evaluation were associated with a good clinical result after surgery. The operation was considered successful in 30 (65 percent) of the 46 patients. Success was not related to the details of the patient's symptoms, the visible appearance of the gastric mucosa at endoscopy or the extent of histologic abnormalities in a preoperative biopsy or resected specimen of gastric mucosa. Therefore, the outcome of surgery could not be predicted from preoperative findings, and gastritis, even though it is often present, is not likely to be responsible for the symptoms in this syndrome. Nevertheless, the results of surgery for postgastrectomy bile vomiting and abdominal pain are good enough that when other conditions have been ruled out, Roux-Y reconstruction can be recommended for patients with severe complaints.

Bile↗
PubMed1980

Pneumatic tourniquet as a substitute for vascular clamps in distal bypass surgery.

The pneumatic tourniquet is an effective substitute for vascular clamps in tibial and popliteal artery surgery. Intimal trauma due to clamping is avoided. Because circumferential dissection of the vessel is not necessary, the vasa vasorum are preserved minimizing ischemic injury to the vessel wall. The technique has been employed in 40 distal popliteal and tibial reconsteal and tibial reconstructions during the past year with only one complication that may possibly be related to its use. Early patency was 92% at the patient's time of discharge from the hospital. In all four patients requiring below-knee amputation, primary wound healing and successful prosthetic rehabilitation were achieved. This technique appears to be safe and simplifies distal reconstructions for lower extremity ischemia.

Arteries↗
PubMed1978

Maintenance of viable arterial allografts by cryopreservation.

An experimental study, designed to investigate the feasibility of maintaining fresh, viable arterial allografts by cryopreservation, is presented. Cryopreserved femoral arterial allografts were shown to be equal in patency rate when compared with fresh controls. The cryopreserved allografts were shown to be superior to fresh allografts in the parameters of intimal integrity, absence of host rejection, and reduced surface thrombogenicity. This experimental study supports the thesis that cryopreservation in liquid nitrogen, utilizing 15% dimethyl sulfoxide (DMSO) and methylprednisolone as a cryoprotectant solution, is an excellent method of preserving and storing fresh allograft arteries for use as a small vessel replacement.

Animals↗