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Biomedical subjects

C H Dohlman

Publications and source records attributed to C H Dohlman.

At least 127 records · Page 7Linked to original sources
PubMedDate not supplied

Morphologic characteristics of posterior polymorphous dystrophy. A study of nine corneas and review of the literature.

Based on their own study of nine corneas with clinically documented posterior polymorphous dystrophy and a review of the literature, the authors describe the morphologic features of this entity. Study by phase contrast light microscopy and transmission and scanning electron microscopy found that changes were primarily in the endothelium and consisted of endothelial cell degeneration and loss with focal fibroblastic and epithelial-like cell transformation. Secondary alterations of Descemet's membrane were seen; they consisted of abnormal lamination with deposition of abnormal collagen material, particularly in the posterior collagen layer, and formation of guttate excrescences and pits.

Adult↗
PubMedDate not supplied

Epithelial downgrowth--fistula repair and keratoplasty.

Eight patients with leaking fistulas from epithelial downgrowth were repaired by various techniques. Wide excision of the fistula and replacement with a graft, followed by a conjunctival flap, proved to be the most satisfactory technique for dealing with the fistula. However, this subset of patients responded to fistula closure with a much worse secondary glaucoma than downgrowth patients in general. Fifteen patients with proven epithelial down-growth received penetrating keratoplasty. Eleven of these grafts failed within a year, but there was no regrowth of epithelium on the back of the graft in at least two patients. In spite of generally discouraging results, we recommend immediate closure of epithelialized fistula to avoid even more severe complications in the future. We also recommend keratoplasty, repeated if necessary, in severe corneal edema. Both situations may eventually require radical glaucoma surgery and/or keratoprosthesis.

Adult↗