The encephalopathy of Reye's syndrome is frequently complicated by increased intracranial pressure (ICP) which may lead to death or severe neurologic sequelae. An understanding of the pathophysiology of increased ICP is necessary to prevent further increases in pressure and to reduce pressure while maintaining adequate cerebral perfusion. Four of seven children with Reye's syndrome and increased ICP survived after reduction of increased ICP by controlled hyperventilation and osmotherapy while being monitored with the Richmond intracranial bolt. Careful anesthetic and critical-care management, appropriate, reliable monitoring, and pentobarbital therapy may constitute the most successful therapy to date for patients with Reye's syndrome and increased ICP.

Anesthesia↗

PubMed1978

Post-operative apnoea caused by breath-holding spells.

After recovery from anaesthesia for a urological procedure a two-and-a-half-year-old child with a history of breath-holding spells became apnoeic and cyanotic in the immediate post-operative period. The pathophysiology of breath-holding as the cause of the apnoea is discussed. Management includes ventilation with oxygen and avoidance of inappropriate treatment with drugs to reverse muscle relaxants or narcotic anesthetics.

Apnea↗

PubMed1978

Anesthetic management of conray toxicity.

Conray (meglumine iothalamate), the contrast media frequently used in shuntograms for diagnosing malfunctioning ventriculo-peritoneal shunts, will occasionally cause severe muscular spasms and seizures. In this article, the authors describe anesthetic and critical care management of a case with this complication.

Anesthesia, Inhalation↗

PubMed1977

Anesthetic management of patients with epidermolysis bullosa.

Presented is a 12-year-old girl with epidermolysis bullosa who required anesthesia for extensive dental rehabilitation. Patients with epidermolysis bullosa can be given anesthetics with minimal complications if the preoperative evaluation is complete, the selection of anesthesia is appropriate, and certain procedures which cannot be safely used in patients with this disease are conscientiously avoided.

Anesthesia, Dental↗

PubMed1974

Dandy-Walker syndrome: spectrum of congenital anomalies.

Explore the source record for details and available documents.

Adult↗

PubMed1973

The electroencephalogram after resuscitation of cardiocirculatory arrest.

Fifty-two EEGs of 31 patients were studied after resuscitation from cardiac arrest. Examples of patients with normal or mildly abnormal (category I) and severely abnormal (category II) EEGs are presented. All patients in category II died. In the patients of category I, EEGs showing no improvement or worsening indicated a fatal prognosis and possibly reflected deteriorating cardiac function caused by the basic disease process.

Adult↗

PubMedDate not supplied

Covert seizures as a cause of postoperative apnea.

Covert seizures expressed as apnea may occur in the immediate postoperative period, and they should be suspected particularly in the known seizure-disorder patient. Management includes ventilation with O2 and avoidance of inappropriate administration of reversal drugs.

Apnea↗