Biomedical subjects
Publications and source records attributed to C H Martone.
A study is presented, which investigates the position of fusion between the buccal and lingual cortical plates. The knowledge of this position will direct the placement of horizontal medial osteotomy in modified sagittal split osteotomy.
Sixty-three human cadaver hemimandibles of known sexual origin were studied. The anatomic relationship between the midpoint of the waist of the lateral ramus and the mandibular foramen was examined and compared with that of the antilingula. No statistical differences were found between either these two landmarks or the sexes.
Since osteomyelitis can occur concurrently with osteopetrosis, all craniotubular bone disorder patients should be treated carefully. We recommend preoperative antibiotic coverage and minimizing any excessive force to avoid the risk of osteomyelitis and jaw fractures when surgery is necessary.
A case of an oral heterotopic gastrointestinal cyst of the tongue is described and a review of the literature is presented. The oral gastrointestinal cyst is a developmental lesion found more commonly in males, with a wide age range, but mostly occurring in the young. It presents as an asymptomatic swelling and most likely arises from misplaced embryonal tissue. Conservative surgical excision is the treatment of choice and no recurrence is expected.
Methohexital is an ultrashort-acting barbiturate widely used in dentistry because of its rapid onset, predictable effects, and short duration of action. Like other barbiturates, methohexital exerts its effects through the gamma-aminobutyric acid (GABA) receptor complex. By binding to its own receptor on the complex, methohexital augments the inhibitory effect of GABA on neurons and additionally can exert a similar effect independent of GABA. After intravenous injection, maximal brain concentrations are achieved within 30 sec and then quickly fall as the drug is redistributed to other tissues, yielding a duration of action after a single dose of 4 to 7 min. Hepatic metabolism accounts for elimination of the drug. Methohexital at conventional doses in healthy individuals is a mild respiratory depressant with modest cardiovascular effects. Adverse effects, however, can include apnea, cardiovascular depression, laryngospasm, hiccough, and allergic-like reactions. Although more recently introduced drugs, such as midazolam, etomidate, and propofol, have specific advantages, methohexital remains a drug of choice for dental outpatient anesthesia because of its low cost, rapid onset, short duration, lack of secretory or emetic properties, and proven history.