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Biomedical subjects

C H Splieth

Publications and source records attributed to C H Splieth.

8 recordsLinked to original sources

Effectiveness of sealants in adolescents with high and low caries experience.

The aim of this 3-year longitudinal study was to analyze caries increment and the caries-preventive effect of sealants in adolescents in the setting of the German national health system. 434 pupils (193 male, 241 female) took part in compulsory school examinations at age 12 (mean 12.3 +/- 0.4 years) and 15 (mean 15.6 +/- 0.3 years) according to WHO criteria, including the examination of sealants. Mean DMFT increased from 1.78 (+/- 2.15) to 3.97 (+/- 3.68), mean DMFS from 2.79 (+/-4.07) to 6.94 DMFS (+/- 8.34), respectively. Logistic regression analysis showed that high caries incidence at the individual level was mostly associated with the type of school ('Gymnasium', RR = 0.3), gender (female, RR = 2.08) and high baseline DMFS (RR = 1.2 per surface), but not with the number of sealants. In an interaction model, adolescents with high baseline DMFS values had an even higher risk of caries increment with an increasing number of sealants compared to adolescents with fewer sealants (p = 0.047). At the tooth level, this effect was detected for first permanent molars, while sealants in premolars and second permanent molars did not result in a statistically significant caries-preventive effect due to the low caries incidence on these surfaces. Thus, sealants on occlusal surfaces of first permanent molars were only protective in individuals with low or moderate caries activity (p = 0.006), which indicates the need for other measures to reduce caries activity in high risk adolescents. In addition, rates of 19% lost sealants and 18% carious or filled surfaces in 3 years suggest a discrepancy between sealant retention under real-life conditions and the results of controlled clinical trials.

Adolescent↗

Chemo-mechanical dentine caries removal with Carisolv using a rotating brush.

AIM: The aim of this study was to assess the efficacy of removing dentine caries using carbide burs, Carisolv with hand instruments and Carisolv in combination with a new mechanical excavation method using a rotating brush. METHODS: 36 extracted permanent teeth, with dentine caries, were assigned into 3 groups according to caries removal technique. Caries removal was monitored by checking the properties of the dentine with a dental explorer. After embedding and sectioning (400 microm), remaining caries was assessed by using a caries detector. In microscope images (7x) of the samples, the mean stain depth of the remaining carious tissue per tooth was calculated by AnalySIS computer software. RESULTS: Four to 8 applications (mean time = 10.9 min) of Carisolv were necessary for caries removal with the new method using rotating brushes. The mean thickness of residual dentine caries by this procedure (226 microm, +/- 136) was higher than the one using Carisolv with hand instruments (57 microm, +/- 39) or carbide burs (32 microm, +/- 20). Even in areas with good access to the lesion, an unacceptable amount of residual caries was observed. CONCLUSION: Thus, it seems that Carisolv using rotating brushes does not reach the degree of caries removal reached by additional mechanical abrasion of Carisolv using hand instruments or conventional rotating carbide burs.

Coloring Agents↗

Evaluation of disparities in physical development and dental age of two specific groups of boys.

AIM: The aim of the study was to investigate potential differences between the physical development and the dental age in two groups of male pupils from two schools with different socio-economic profiles in the city of Torun (Poland). MATERIALS AND METHODS: A total number of 286 school boys (age: 9-12 years) was examined: Group A consisted of 104 pupils of a private school (mean age: 10.36-/+0.1 years), group B were 182 normally intellectually developed, non-handicapped pupils (10.59-/+0.1 years) of a therapeutic school for children with specific learning difficulties like dyslexia, dysgraphy, ADHD or severe speech disorders. The parameters of the physical development (body height, body weight) and the dental age assessed by eruption were evaluated based on a biological frame of reference and percentile charts. RESULTS: The two groups showed distinct disparities in physical and dental development: the mean values of body height were significantly higher in group A than group B (p<0.02). In addition, differences in percentile distributions of body height, body mass and dental age showed statistical significance (p<0.001, 0.01 and 0.01, respectively). The relationship between body height/body mass and dental age was not statistically significant (p>0.3). CONCLUSION: The pronounced disparities concerning physical and dental development within boys of different socio-demographic background should be taken into account by health professionals. No correlation was found between physical and dental development.

Body Height↗

The effect of a polyhexamethylene biguanide mouthrinse compared with a triclosan rinse and a chlorhexidine rinse on bacterial counts and 4-day plaque re-growth.

OBJECTIVES: For various clinical applications, polyhexamethylene biguanide hydrochloride (PHMB) has been used for many years as an antiseptic in medicine. Recently, a 0.04% and a 0.12% PHMB mouthwash were shown to inhibit plaque re-growth and to reduce oral bacterial counts. In this study, a 0.2% PHMB mouthrinse (A) was compared with a positive control 0.12% aqueous chlorhexidine solution (B), a commercially available 0.3% triclosan/2.0% polyvinyl methyl ether maleic acid copolymer mouthrinse (Colgate Total Plax) (C), and a negative control placebo rinse (10% ethanol, flavour) (D). MATERIALS AND METHODS: The controlled clinical study was a double blind, randomized, four replicate cross - over design. Plaque re-growth was assessed with the Turesky et al. (1970) modification of the Quigley & Hein (1962) plaque index. The antibacterial effect was assessed by taking bacterial counts on the tooth surface (smears from the buccal surface of 16/26) and mucosa (smears from the buccal mucosa in opposite of area 16/26) after the professional prophylaxis and after the first rinse with the preparations on day 1 and prior to the clinical examination on day 5. Sixteen volunteers participated and, on day 1 of each study period were rendered plaque-free, ceased toothcleaning, and rinsed twice daily with the allocated mouthrinse. On day 5, plaque was scored and smears were collected according to the protocol. A 10-day wash-out period was carried out between each rinse evaluation. Data were analysed using ancova with Bonferroni HSD adjustment for multiple comparisons (colony forming units per sample) with a significance level alpha=0.05. RESULTS: The 0.2% PHMB mouthrinse (A) was significantly better at inhibiting plaque than the placebo (D), but significant less effective than the 0.12% aqueous chlorhexidine solution (B). There is no significant difference between A and the 0.3% triclosan/2.0% copolymer mouthrinse (C). Bacterial count reductions (tooth surface and mucosa) with PHMB (A) were significantly greater compared with the placebo (D) and triclosan (C), but significantly lower compared with chlorhexidine (B) (tooth surface) and equally effective compared with chlorhexidine (B) (mucosa). CONCLUSION: Consistent with previous studies, a PHMB mouthrinse was shown to inhibit plaque re-growth and to reduce oral bacterial counts, indicating that PHMB could be an alternative to established mouthrinses in preventive applications.

Adult↗

Caries prevention programs for groups: out of fashion or up to date?

After a caries decline of about 80% in children in Western Europe and other industrialized countries, there should be critical debate about the best way for future caries prevention. Multiple fluoride use played an important role in caries reductions achieved in the 1980s and 1990s, but it also resulted in a polarization of lesion distribution in young people: the majority consists of low-caries or even lesion-free individuals, while a minority is a so-called high caries risk group which seems not to be open to preventive programs. Recent studies indicate that frequent fluoride applications (>6 times/year) in conjunction with effective plaque removal can be a successful approach for effective future caries prevention in high caries risk groups. Health promotion programs that are merely educational and do not provide fluoride do not seem to be effective. Alternatively, preventive measures could be performed at home or in a private practice, but only minimal compliance is reached in high risk groups compared with out-reaching group programs. Thus, group programs are instrumental in providing effective and efficient caries-preventive measures in children. The more expensive time of a dental practice team should be limited to procedures where costly equipment is needed (professional tooth cleaning, sealants, etc.). For efficient caries prevention, measures formerly targeted specifically at either populations, groups, or individuals should be remodeled and aimed to interact in order to achieve optimal oral health in children at a reasonable cost.

Cariostatic Agents↗

Comparison of measurements obtained with hand files or the Canal Leader attached to electronic apex locators: an in vitro study.

AIM: The aim of the present in-vitro study was to combine directly the Canal Leader handpiece (SET, Olching, Germany) with the electronic apex locators ROOT ZX (Morita, Kyoto, Japan) and JUSTY (Yoshida, Tokyo, Japan) to find out whether the working length values thus obtained were identical to those resulting from the combination of the same electronic devices with hand files. METHODOLOGY: A total of 50 natural extracted teeth with single canals and mature apices were used. A radiograph was used as a control and the distance from the radiographic apex to the tip of the file was measured and compared with the results of the electronic length determination. RESULTS: For both electronic devices the differences amongst the distribution of the measurements were not statistically significant under the specified conditions (P > 0.05), indicating that the measurements with hand files and with the Canal Leader were identical for the majority of the cases. CONCLUSIONS: Under the conditions of this study the working length of canals obtained with electronically assisted hand files were similar to those obtained with the electronically assisted mechanical handpiece Canal Leader.

Dental Equipment↗

Efficacy of occlusal plaque removal in erupting molars: a comparison of an electric toothbrush and the cross-toothbrushing technique.

The aim of this prospective crossover study was to compare the efficacy of two methods of plaque removal on partially erupted occlusal surfaces, which comprise about 80% of the sites affected by caries in schoolchildren. After a baseline examination, 16 children (aged 5-7 years) and their parents were instructed in cleaning the occlusal surface of an erupting molar either with an electric toothbrush or with a manual toothbrush in the cross-brushing technique. After 2 weeks, the proportion of the occlusal surface covered by plaque was measured again using the occlusal plaque index, a new, highly reproducible method (intraclass correlation coefficient > 0.90). For the next 2 weeks, they used the other technique. In the multifactorial variance analysis, the individual child and parents were the most important factor for the amount of plaque present. Secondly, both methods resulted in about 50% less plaque on occlusal surfaces compared to baseline (29.2%) with a slightly but significantly smaller mean value for the electric toothbrush (14.7%, manual cross-brushing technique 16.7%; p = 0.025).

Analysis of Variance↗

Responder and nonresponder analysis for a caries prevention program.

To be able to generalize studies, it is important to know whether responders and nonresponders differ significantly. These data are usually not available. To assess whether responders and nonresponders differed significantly, 319 first and second graders in Greifswald, Germany took part in a compulsory dental school examination. Their parents completed a questionnaire on oral health topics and were asked to decide about their children's participation in a school-based caries prevention program plus anonymous scientific evaluation. The 91 children who were not allowed to participate (nonresponders) were older (mean 8.5 years) than the 228 responders (mean 8.1 years; p < 0.001), mostly because of a few older children having repeated a grade. In an age-adjusted analysis, nonresponders exhibited in 21 of 30 indices of higher caries and plaque values, less preventive measures and a lower rate of participation. The difference in caries in the permanent dentition and fluorosis reached statistical significance. This study suggests that nonresponders to caries prevention programs might comply less with preventive measures and exhibit poorer oral health than responders: a result which has to be taken into account in research and prevention programs in the community.

Age Factors↗