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Biomedical subjects

C H Yoon

Publications and source records attributed to C H Yoon.

53 records · Page 3Linked to original sources
PubMedDate not supplied

The prevalence of congenital inverted nipple.

To investigate the prevalence and type of congenital inverted nipple, and realizing that the condition is a disease for which treatment is necessary, 1,625 unmarried women aged between 19 and 26 were physically examined and responded to questions about inverted nipple. Fifty-three of 1,625 subjects (3.26%) presented with this malformation, and it was found in 3.05% of the 3,250 nipples examined. In 46 of the 53 (86.79%), the condition was bilateral, and in 7 (13.21%), it was unilateral. In such cases, inversion was found on the right side in two subjects and on the left side in five. Of the total number of congenital inverted nipples, 96.23% were umbilicated and 3.77% were invaginated. Nine of the 53 subjects with inverted nipple considered that the condition should be corrected. Prior to counseling and possible surgery, the medical practitioner must carefully consider all available information, and the data contained in this report may thus be useful.

Adult↗
PubMedDate not supplied

Congenital lacrimal system obstruction: treatment with balloon dilation.

PURPOSE: To evaluate the safety and effectiveness of balloon dilation for the treatment of congenital lacrimal system obstruction. MATERIALS AND METHODS: Fluoroscopically guided balloon dilation was attempted in 20 eyes of 16 patients with an age range of 12-78 months (mean, 33 mo) for congenital lacrimal system obstruction. Fifteen eyes had complete obstruction at the valve of Hasner, three eyes had completely obstruction at the junction between the lacrimal sac and the nasolacrimal duct, and two eyes had partial obstruction at the nasolacrimal duct. Under general anesthesia, a ball-tipped guide wire was introduced through the superior punctum into the inferior meatus of the nasal cavity and pulled out through the naris with use of a hook. A deflated 3-mm-diameter balloon catheter was then advanced in a retrograde direction and the balloon was dilated. Every patient underwent an ophthalmic evaluation before the procedure and was scheduled to be followed with office examination at 1, 3, and 6 months after the procedure. RESULTS: There were no major complications. "Technical success" was defined as free passage of contrast medium through the entire lacrimal system to the nasal cavity. The procedure failed in one eye. After balloon dilation, all 19 eyes in which technical success was achieved showed improvement of epiphora. During the follow-up period of 2-33 months (mean, 16 mo), all eyes maintained improvement of epiphora and needed no further treatment. CONCLUSION: Balloon dilation is a safe and effective therapeutic technique for the treatment of congenital lacrimal system obstruction.

Catheterization↗
PubMedDate not supplied

Linkage group IV in the Syrian hamster: spontaneous seizure and jute.

It was shown that sz and J are closely linked and that the recombination frequency between these two genes is 7.41 +/- 2.91. It was also shown that J is not linked with markers in linkage groups I and III, and that sz is not linked with a marker in linkage group II. Therefore, linkage between sz and J is a new linkage group. Since only three linkage groups have so far been established in the Syrian hamster, linkage groups I, II and III, this new linkage constitutes linkage group IV.

Animals↗
PubMedDate not supplied

Five new mutations in the Syrian hamster: furloss, fur-deficiency, juvenile gray, ashen, and quaking.

Five new mutations in the Syrian hamster are described: furloss, a simple recessive trait affecting the quality of hair; fur-deficiency, a simple recessive trait affecting the quantity of hair and longevity; juvenile gray, a simple recessive trait affecting coat color and body size; ashen, a semidominant trait affecting both coat color and quantity of hair; and quaking, a simple recessive trait affecting motor activity. Gene symbols, fs, Rfd, jg, A, and q are proposed for these mutations.

Alopecia↗
PubMedDate not supplied

Immature gastric teratoma in an infant: a case report.

Gastric teratomas are extremely rare neoplasms and almost exclusively benign. They occur predominantly in males and generally present as a palpable abdominal mass. To our knowledge, only one adult case has been described in the Korean literature. We report a case in which an immature gastric teratoma in a 3-month-old boy was revealed by CT and US.

Humans↗
PubMedDate not supplied

Magnetic resonance imaging and proton magnetic resonance spectroscopy in neuro-Behçet's disease.

OBJECTIVE: Neuro-Behcet's disease (NBD) is one of the most serious complications of Behcet's disease (BD). Proton magnetic resonance spectroscopy (1H MRS) has been proved to be useful in detecting neuro-metabolic abnormalities in various diseases affecting the brain. In this study, we attempted to characterize the magnetic resonance imaging (MRI) findings in Korean patients with NBD and then examined the usefulness of 1HMRS in evaluating the MRI-negative brain area of NBD patients. METHODS: We performed brain MRI in 18 BD patients with neurologic symptoms and signs. Seven NBD patients without thalamic lesions and 8 healthy controls underwent brain 1H MRS, in which an 8 ml voxel was placed in the left thalamus and the N-acetylaspartate (NAA)/creatine (Cr) ratio was measured. RESULTS: Fourteen of 18 BD patients were diagnosed as having NBD and 12 NBD patients (86%) had brain lesions on MRI. Most lesions were of high signal intensity on T2-weighted images and located in the midbrain, pons, basal ganglia, and white matter. On 1H MRS, the thalamic area without gross abnormalities on MRI showed a significantly lower NAA/Cr ratio in NBD patients compared to healthy controls (1.07 +/- 0.08 versus 1.54 +/- 0.27, P < 0.01). In 2 NBD patients, the NAA/Cr ratios, monitored serially, were normalized along with clinical improvement 6 months after treatment with prednisolone and immune suppressive agents. CONCLUSION: MRI is a very sensitive diagnostic method for NBD, and 1H MRS may be useful for the early detection and follow-up of MRI-negative NBD.

Adult↗