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C Harz

Publications and source records attributed to C Harz.

8 recordsLinked to original sources
PubMed2001

[Impact of different iodine concentrations on abdominal enhancement in biphasic multislice helical CT (MS-CT)].

UNLABELLED: Impact of different iodine concentrations on abdominal enhancement in biphasic multislice helical CT (MS-CT). PURPOSE: To evaluate if different iodine concentrations of a contrast material (c.m.) have an impact on abdominal enhancement in MS-CT during the arterial (AP) and portal venous phase (PVP). MATERIALS AND METHODS: 75 patients underwent biphasic CT of the abdomen. They were assigned to three equally sized groups. For all patients a non-ionic c.m. (iopromide, Ultravist, Schering AG, Berlin) with different iodine concentrations and a constant total iodine load of 37 g with an injection flow rate of 4 ml/s was used. The volume of the c.m. differed depending on the iodine concentrations: group 1 (123 ml of 300 mgl/ml); group 2 (112 ml of 335 mgl/ml); group 3 (100 ml of 370 mgl/ml). The scan delay was optimized by using a bolus tracking device. The groups were compared concerning their mean enhancement of aorta, spleen, pancreas, and liver in the AP and PVP. RESULTS: The comparison of the three groups showed an improved enhancement in aorta, spleen, and pancreas during the AP by using the higher c.m. concentrations. In the PVP the c.m. enhancement of aorta, liver, spleen, and pancreas was independent of the administered c.m. concentration. CONCLUSION: Higher iodine concentrations of c.m. have a positive impact on abdominal enhancement during the AP. The concentration has no influence on the enhancement during the PVP of abdominal MS-CT.

Adult↗
PubMed2001

[Common bilio pancreatic channel syndrome in adults].

BACKGROUND: The Common Channel Syndrome (CCS) is defined as the union of the biliary and pancreatic ducts outside of the duodenal wall with a common duct more than 15 mm long. It is classified morphologically in types 1 and 2, whether it is the biliary or the pancreatic duct the one that predominates. CCS is uncommon in Western countries. It is described particularly in children and has not yet been reported in Chile. AIM: To report the frequency of CCS among patients subjected to endoscopic retrograde cholangiopancreatography (ERCP). PATIENTS AND METHODS: Between 1992 and 1998, 1860 ERCPs were performed for the diagnosis of biliary or pancreatic diseases. RESULTS: In six patients (0.35%) a CCS was diagnosed (3 type 1 and 3 type 2). All patients presented with pain and three with jaundice. Four patients had a previous cholecystectomy, three due to cholelithiasis and one due to gallbladder cancer. A common bile duct resection and bilioenteric anastomosis was done in three patients with a favorable outcome. Two patients with an advanced age and one with a gallbladder cancer, were not operated. CONCLUSIONS: CCS was found in 0.35% of patients subjected to an ERCP. It frequently presents in association with one or more bilio-pancreatic diseases: cholelithiasis, choledocolithiasis, cholangitis, pancreatitis and gallbladder cancer. Resection of the common bile duct and a bilio-enteric anastomosis is proposed as the surgical treatment.

Adult↗
PubMed1993

Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution, and probability of detection in routine histologic samples.

BACKGROUND: Gallbladder diseases, especially cholelithiasis, are extremely frequent in Chile, and an increasing frequency of gallbladder carcinoma has been observed during the last decades. Hyperplastic and atypical epithelial lesions of gallbladder epithelium have been considered potential precursors of invasive carcinoma. The current study was designed to study the frequency, distribution, extension, and probability of routine detection of potentially preneoplastic changes of gallbladder epithelium. METHODS: Epithelial changes were histologically studied by mapping gallbladders obtained at elective cholecystectomy for lithiasis in 162 Chilean patients. RESULTS: Antral-type metaplasia was found in 95.1% of the cases, intestinal metaplasia in 58.1%, hyperplasia in 46.9%, dysplasia in 16%, and carcinoma in situ in 2.5%. A significant association of intestinal metaplasia with hyperplasia, intestinal metaplasia with dysplasia, and hyperplasia with dysplasia was found. Hyperplasia and dysplasia were also present in four cases with carcinoma in situ. Mean extension of the lesions (percentages of the sections in which the change was observed) was antral-type metaplasia (62.7%), intestinal metaplasia (25.3%), hyperplasia (24.1%), dysplasia (15.5%), and carcinoma in situ (9.7%). Antral-type and intestinal metaplasia were more extensive and more severe in patients older than 50 years of age. Hyperplasia was more extensive in cases in which it was associated with dysplasia and carcinoma in situ. CONCLUSIONS: The extension of metaplasia seems to depend in part on the age of the patients. The association of intestinal metaplasia with hyperplasia and dysplasia agrees with the findings of other authors that relate metaplasia to gallbladder cancer. The epithelial lesions are focal or partially confluent, thus a single random histologic section will detect less than one third of the hyperplasias, dysplasias, and carcinomas in situ.

Adult↗
PubMed1993

[Multiple splenic abscesses. Report of 2 cases].

Splenic abscesses are infrequent and usually associated to sepsis and immunodepression. The diagnosis is commonly made in the necropsy. We report two cases of multiple splenic abscesses in type II diabetic patients that were diagnosed by ultrasound. Both patients were successfully managed with surgery (drainage of left subphrenic space in one and splenectomy in the other) and antimicrobial agents.

Abscess↗
PubMed1991

Extracorporeal shock-wave lithotripsy and endoscopy: combined therapy for problematic bile duct stones.

Endoscopic treatment of bile duct stones is currently successful in 86% of patients. We prospectively studied the efficacy and complication rate of extracorporeal shock-wave lithotripsy (ESWL) of problematic bile duct stones combined with endoscopy. When stone removal was not possible, patients were subjected to ESWL. Fragmented stones were removed endoscopically. During 1 year, 220 patients presenting with choledocholithiasis were diagnosed and 188 were successfully treated endoscopically. In all, 3 subjects received alternative treatment and the remaining 29 (13%) constituted our study group; 19 (65%) were women and the mean age was 76.7 years. Overall, 22 (76%) were high-risk patients; 23 (79%) were jaundiced and 9 (31%) had cholangitis at admission. The most frequent indication for ESWL was stone size. Stone fragmentation was achieved in 80% of cases. Complications were mild and were managed conservatively. No patient died. Complete stone clearance was possible in 23 (80%) cases. The association of ESWL and endoscopy enhanced the success rate of endoscopic stone clearance from 86% to 96%. During the same period, open surgery was performed in 4 cases for residual common bile duct (CBD) stones and in 32 cases in association with simultaneous cholecystectomy.

Aged↗