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Biomedical subjects

C Herrmann

Publications and source records attributed to C Herrmann.

At least 127 records · Page 7Linked to original sources
PubMed1978

Computer tomography of the anterior mediastinum in patients with myasthenia gravis and suspected thymoma.

Six patients with myasthenia gravis and suspected thymoma underwent radiologic investigation using plain chest radiography, conventional anterior mediastinal tomography, and computed tomography. All underwent exploratory thoractomy within 1 month of the radiologic workup. In three of the five cases that proved to be thymoma, CT yielded significant diagnostic information that bore directly on the management and/or prognosis of the patient. We therefore believe that CT may be a valuable adjunct in the radiologic investigation of the patient with myasthenia gravis.

Adolescent↗
PubMed1978

[Quantitative examinations of stellate cells in the region of the cingulate gyrus in the rat].

Brains of three months old male rats were handled by a modified Golgi-Kopsch method. Stellate cells of the gyrus cinguli were drawn, classified into four types and analyzed quantitatively. The values of the four types were compared by means of a varianz analysis. The four types are: isodendritic stellate cells without spines (I/OS), isodendritic stellate cells with spines (AI/OS), anisodendritic stellate cells without spines (AI/OS), anisodendritic stellate cells with spines (AI/MS). Type I/OS and type AI/MS are the most contrary one. Main results are: 1. The lengths of the dendritic branches show maximum values in the 3rd order. The dendritic lengths exhibit great deviations in all the four types. The alteration of the lengths values from one to the next order is similar the basal dendritic tree of primitive pyramidal neurons. The same analogy you can find for the dendritic numbers of corresponding orders: highest numbers are in the 2nd order, in the following orders the numbers decrease permanently. Isodendritic stellate cells without spines have significantly more dendrites of the 1st order compared with the other three types. 2. The branching pattern --- revealed in the number of free dendritic endings --- shows differences between isodendritic stellate cells without spines and anisodendritic stellate cells with spines. 3. The total lengths of the dendritic branches and the lengthes of the single dendritic fields are similar in significant differences: least lengths there are in anisodendritic stellate cells with spines, they are significantly different from isodendritic stellate cells with and without spines. 4. There are differences in the values of spines and varicosities between all types which causes the possibility of classifying stellate cells according to this parameter. This is valid for spines values of the orders, spines values of single dendritic fields and for the total number of spines for one neuron. 5. Localization and extending in the layers: most stellate cells extend through several layers. The isodendritic type is preferentially localizes in layer III, the anisodendritic one in layer V.

Animals↗
PubMed1977

[Demonstration of antibody-coated bacteria in the urine of pregnant women].

Urinary sediments of 64 pregnant women with significant bacteriuria which has been demonstrated several times before, have been investigated for the presence of antibody coated bacteria. Antibody titers were determined in the corresponding serum samples in addition and the results were compared with the clinical diagnosis. In 50% of pregnant women with pyelonephritis antibody coated bacteria could be demonstrated, while 60% of them had elevated serum titers. Taking into account both results in 80% of the pregnant women the clinical diagnosis of pyelonephritis could be confirmed. Pregnant women with asymptomatically significant bacteriuria never gave positive results, whereas pregnant women with cystitis mainly did have negative results. The demonstration of antibody coated bacteria in the urinary sediments of pregnant women with significant bacteriuria as well as the detection of elevated serum antibody titers with the indirect immunofluorescence technique against the urinary strain were found to be of importance for the valuation of a significant bacteriuria.

Antibodies, Bacterial↗
PubMed1976

[Ambulatory tocography].

The value of the ambulant tocography was tested in 127 cases by ambulant tocograph T 500. The average frequency of uterine contractions was in 66 normal cases 0,5/30 min. This frequency of uterine contraction was higher in a group with anamnestic risk (1,1/30 min) and in patients with tocolytic medication (2,3/30 min). Nearly term all groups tended to higher frequency of uterine contractions. The ambulant tocography is a new method to completed the diagnostic.

Ambulatory Care↗
PubMed1975

Myasthenia gravis and invasive thymoma: a 20-year experience.

In 20 years, 19 patients with myasthenia gravis and invasive thymoma have been seen by the Neurology Service at the UCLA Center for Health Sciences. This represents 4 percent of 493 myasthenia gravis patients seen during the same time and 37 percent of myasthenic patients with thymomas. Eight are still alive and 11 have died. Fifteen patients had the onset of myasthenic symptoms before discovery of the thymoma, while only four patients had chest symptoms and/or radiographic evidence of an anterior mediastinal mass prior to the onset of weakness. Radical excision of the tumor, if possible, and the remaining thymus, high dosage alternate day prednisone, and radiation therapy, if indicated, seem the treatments of choice. Recurrences of tumor nodules may necessitate further local radiation or the use of cytotoxic agents.

Adult↗
PubMed1975

Leukocyte and lymphoid cell counts in myasthenia gravis.

Serial leukocyte counts and lymphoid cell counts were compared before and after thymectomy via sternal-splitting incision in 50 patients with myasthenia gravis. Leukocyte counts and lymphoid cell counts of the thymectomized patients also were compared to those of 30 non-thymectomized myasthenic patients and 150 non-myasthenic patient controls. While mean leukocyte counts did not change significantly before and 5.5 plus or minus 5 years after thymectomy, mean lymphoid cell counts were slightly lower during this observation period post-thymectomy (t equals 1.918, p equals 0.03). Lower lymphoid cell counts appeared to correlate with a favorable response of myasthenia gravis in patients with thymic hyperplasia and mainly involuted thymus.

Adolescent↗