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Biomedical subjects

C Hertzog

Publications and source records attributed to C Hertzog.

At least 19 recordsLinked to original sources

Factors related to medication adherence in memory disorder clinic patients.

Medication adherence is a substantial problem in the elderly. It may be even more important among elderly persons with memory problems, since other factors that lead to non-adherence may be compounded with the memory problems themselves. The objective was to determine whether a model that integrates research on medication adherence from several research domains is useful in understanding adherence in elderly patients. The methodology involved a cross-sectional observational study using a convenience sample of 63 patients drawn from a university-affiliated outpatient memory disorders clinic. The primary measure of medication adherence was caregivers' reports of patients' medication adherence. Patients and their caregivers were asked questions assessing their beliefs about the seriousness of each condition for which a medication was prescribed and the likely outcome of that condition without treatment. Additional data collected included presence of side effects, total number of medications taken, and patients' mood and cognitive status. Multilevel path analysis confirmed several model-based predictions. Caregivers' reports of adherence were predicted by estimates of disease outcome, the presence of side effects, and patients' relying on themselves to remember to take medications. Results partially confirm the integrative model in understanding medication adherence in these patients. Patients' beliefs about the likely effect of medication treatment for their condition and the presence of side effects influence reported medication adherence. Results thus suggest that efforts to educate patients about the likely response of their medical condition to treatment and to assess and deal with medication side effects might improve patient adherence.

Aged↗

Beyond a stereotyped view of older adults' traditional family values.

Structural equation models for predictors of traditional family values regarding relationships were examined in 2 samples: undergraduate students and adults ranging widely in age (23-86 years). Predictor variables included verbal ability, need for cognition, need for closure, intolerance for ambiguity, religiosity, and gender orientation. The models accounted for a substantial proportion of the variance in traditional family values (64% for students, 63% for adults). Findings provide little support for common stereotypes regarding age and gender differences in traditionalism. Instead, 3 individual-differences variables predicted traditional family values: need for closure, religiosity, and verbal ability. Outcomes argue for the need to identify multiple mechanisms by which personal characteristics such as need for closure and religiosity influence traditionalism in social belief systems and argue against reliance on status variables such as age and gender as explanatory variables for these beliefs.

Adolescent↗

Well-being as a moving target: measurement equivalence of the Bradburn Affect Balance Scale.

Although the Bradburn Affect Balance scale (ABS) is a frequently used two-factor indicator of well-being in later life, its measurement and invariance properties are not well documented. We examined these issues using confirmatory factor analyses of cross-sectional (adults ages 54-87 years) and longitudinal data from the Victoria Longitudinal Study. Stability of the positive and negative affect factors was moderate across a 3-year period. Overall, factor loadings for positive affect items were invariant over time with the exception of the pleased item. Negative affect items were time invariant. However, age-group comparisons between young-old and old-old groups revealed age differences in loadings for the upset item at Time 1. Finally, gender groups differed in loadings for the top of the world and going your way items. Thus a pattern of partial measurement equivalence characterized item response to the ABS. Our results suggest that group comparisons and longitudinal change in ABS scale scores of positive and negative affect should be interpreted with caution.

Affect↗

Measuring strategy production during associative learning: the relative utility of concurrent versus retrospective reports.

Strategy production during associative learning can be measured by self-reports made either concurrently with study or retrospectively. Both kinds of report presumably have strengths and weaknesses, yet a systematic comparison has not been conducted. Younger and older adults studied paired associates and reported strategy production using one or both kinds of report. Participants either received or did not receive descriptions of mediational strategies prior to study. Retrospective reports were not completely consistent with concurrent reports, suggesting that the validity of retrospective reports is somewhat diminished by forgetting. Making concurrent reports did not affect subsequent retrospective reports, but describing strategies affected reported strategy production for both age groups and paired-associate recall for older adults. A production deficiency constrained older adults' performance when they did not receive strategy descriptions prior to study. Discussion focuses on the relative utility of concurrent and retrospective reports of strategy production.

Adolescent↗

An individual differences analysis of ability and strategy influences: age-related differences in associative learning.

The relationships among abilities, strategies, and performance on an associative learning task were investigated for young (aged 17 to 34) and older adults (aged 60 to 82). Participants received extensive practice on a noun-pair task in which they could use a visual-scanning strategy or a memory-retrieval strategy. Older adults were more likely to use the scanning strategy. Age differences were reduced when comparisons were made only for participants using a retrieval strategy. Associative memory was predictive of learning on the task, and semantic memory access speed was predictive of practiced performance. Practiced performance on a memory-search task that also required associative learning was predictive of practiced noun-pair performance. Models of ability-performance relationships for skill acquisition are discussed.

Adolescent↗

Updating knowledge about encoding strategies: a componential analysis of learning about strategy effectiveness from task experience.

Researchers have argued for age deficits in learning about the effects of encoding strategies from task experience, partly on the basis of absolute accuracy of metacognitive judgments. However, these findings could be attributed to factors other than age differences in learning. Forty older and 40 younger adults participated in 2 study-test trials in which they studied paired associates with imagery or repetition, predicted recall for the items, attempted recall, and postdicted recall. Recall was greater after imagery than repetition, yet this effect was not fully reflected by predictions made on Trial 1. Although both older and younger adults accurately postdicted recall from Trial 1, absolute accuracy of the predictions made on Trial 2 showed little improvement. By contrast, both age groups demonstrated increases in between-person correlations of predictions with recall, which is inconsistent with age deficits in knowledge updating. Thus, both older and younger adults had updated knowledge about the relative effects of the strategies, but such updating was not evident in the absolute accuracy of the predictions.

Adult↗

A multivariate model of gender differences in adolescents' internalizing and externalizing problems.

Gender differences observed in interpersonal and self-critical vulnerabilities, reactivity to stressful life events, quality of relationships, and self-concepts inform a multivariate theoretical model of the moderating effects of gender on internalizing and externalizing problems in adolescence. To test this model, data were collected in a 1-year prospective study from an ethnically diverse sample of 460 middle school students. Increases in girls' internalizing symptoms, compared with boys', were partly explained by greater stability in girls' interpersonal vulnerabilities and greater magnitude in coefficients linking girls' relationships with parents and peers and internalizing problems. Boys' risks for externalizing problems, compared with girls', were partly explained by the greater stability in boys' vulnerability to self-criticism. Coefficients for most pathways in the model are similar for boys and girls.

Adolescent↗

Use it or lose it: engaged lifestyle as a buffer of cognitive decline in aging?

Data from the Victoria Longitudinal Study were used to examine the hypothesis that maintaining intellectual engagement through participation in everyday activities buffers individuals against cognitive decline in later life. The sample consisted of 250 middle-aged and older adults tested 3 times over 6 years. Structural equation modeling techniques were used to examine the relationships among changes in lifestyle variables and an array of cognitive variables. There was a relationship between changes in intellectually related activities and changes in cognitive functioning. These results are consistent with the hypothesis that intellectually engaging activities serve to buffer individuals against decline. However, an alternative model suggested the findings were also consistent with the hypothesis that high-ability individuals lead intellectually active lives until cognitive decline in old age limits their activities.

Adaptation, Psychological↗

Longitudinal changes in quantitative and qualitative indicators of word and story recall in young-old and old-old adults.

The present study examined longitudinal changes in quantitative and qualitative measures of episodic memory. The sample, taken from the Victoria Longitudinal Study, consisted of 158 young-old adults (initially 55 to 70 years old) and 84 old-old adults (initially 71 to 86 years old) who were tested three times over six years. Average word and text recall, as well as five indicators of qualitative aspects of word recall (e.g., number of categories recalled) and one indicator of structure of text recall (i.e., levels of information) were used. For word recall, although both age groups exhibited negative longitudinal changes in quantitative performance, overall qualitative performance was generally stable. Two qualitative indicators (number of categories and intrusions) showed modest decline and one (organization at recall) showed improvement. Results for overall text recall showed significant performance increments for the young-old group, whereas the old-old group exhibited slight declines in overall performance. Analyses of qualitative measures showed stable structure of hierarchical recall, with the old-old being impaired at all levels of detail in the stories. Overall results suggest that some underlying structural characteristics of word and text recall may be maintained into late life even when significant overall decline is observed.

Age Factors↗

Medication adherence in rheumatoid arthritis patients: older is wiser.

OBJECTIVES: To create a profile of individuals nonadherent to their medications in an age-stratified sample (ages 34-84) of community-dwelling rheumatoid arthritis patients. The relative contributions of age, cognitive function, disability, emotional state, lifestyle, and beliefs about illness to nonadherence were assessed. DESIGN: A direct observation approach was used in conjunction with structural equation modeling. All participants were administered a preliminary assessment battery. Medications were then transferred to vials with microelectronic caps that recorded medication events for all medications for the next 4 weeks. PARTICIPANTS AND SETTING: A volunteer sample of 121 community-dwelling rheumatoid arthritis (RA) patients were recruited from newspaper ads, posters, and via informal physician contact from private rheumatology practices in Atlanta and Athens, Georgia. Written verification of the RA diagnosis and a disease severity rating were obtained from personal physicians before patients were enrolled in the study. Patients were tested in a private physician's office, and their medication adherence was monitored electronically for a month in their every-day work and home settings. MEASUREMENTS AND RESULTS: Structural equation modeling techniques were used to develop a model of adherence behavior. Cognitive and psychosocial measures were used to construct latent variables to predict adherence errors. The model of medication adherence explained 39% of the variance in adherence errors. The model demonstrated that older adults made the fewest adherence errors, and middle-aged adults made the most. A busy lifestyle, age, and cognitive deficits predicted nonadherence, whereas coping with arthritis-related moods predicted adherence. Illness severity, medication load, and physical function did not predict adherence errors. Omission of medication accounted for nearly all errors. CONCLUSION: Despite strong evidence for normal, age-related cognitive decline in this sample, older adults had sufficient cognitive function to manage medications. A busy lifestyle and middle age were more determinant of who was at risk of nonadherence than beliefs about medication or illness. Thus, practicing physicians should not assume that older adults have insufficient cognitive resources to manage medications and that they will be the most likely to make adherence errors. Very busy middle-aged adults seem to be at the greatest risk of managing medications improperly.

Adaptation, Psychological↗

Aging and deficits in associative memory: what is the role of strategy production?

A new method was developed to investigate the degree to which age differences in strategy production mediate age differences in paired-associate recall. Participants were instructed to use imagery or any strategy and were to report the strategy produced for each item. Age similarities in reported strategy production were found for related (Experiment 1) and unrelated (Experiment 2) word pairs: Both age groups (a) reported using effective mediators (imagery and sentence generation) more often than using no mediators and (b) complied with instructions to use imagery. Although individual differences in strategy production were related to differences in recall performance, differential strategy production accounted for little of the age differences evident in associative memory.

Adolescent↗

Age-related differences in absolute but not relative metamemory accuracy.

In 3 experiments, the effects of age on different kinds of metacognitive prediction accuracy were assessed. participants made global memory predictions and item-by-item memory predictions in a single experimental task. Metacognitive accuracy was evaluated with correlational and more traditional difference-score measures. Difference-score measures were found, in some cases, to be sensitive to level of recall performance. Correlational techniques revealed that older adults monitored learning effectively. Relative to younger adults, they showed equally accurate immediate judgments of learning (JOLs), produced an equivalent delayed-JOL effect, and showed equivalent upgrading in the accuracy of their global prediction from before to after study of test materials.

Adult↗

Effect of age on event-based and time-based prospective memory.

The magnitude of age differences on event- and time-based prospective memory tasks was investigated in 2 experiments. Participants performed a working memory task and were also required to perform either an event- or time-based prospective action. Control participants performed either the working memory task only or the prospective memory task only. Results yielded age differences on both prospective tasks. The age effect was particularly marked on the time-based task. Performance of the event-based prospective task, however, had a higher cost to performance on the concurrent working memory task than the time-based task did, suggesting that event-based responding has a substantial attentional requirement. The older adults also made a significant number of time-monitoring errors when time monitoring was their sole task. This suggests that some time-based prospective memory deficits in older adults are due to a fundamental deficit in time monitoring rather than to prospective memory.

Adolescent↗

Older and younger adults use a functionally identical algorithm to select items for restudy during multitrial learning.

We investigated whether aging affects several components of how people select items for study during multitrial learning. Younger and older adults studied paired-associate items and then made delayed judgements of learning (JOLs). Immediately after making a JOL for an item, some participants decided whether to restudy the item on subsequent trials; for other participants, the computer selected for restudy the items that had been judged as least-well learned. Next, paired-associate recall occurred, which was followed by restudy-test trials. As expected, age differences occurred in recall on the first trial, and this difference was propagated across trials. In contrast to the hypothesis that older adults would be more conservative in selecting items, both age groups selected to restudy (a) the items that they had rated as least-well learned and (b) the majority of items that would not be recalled on the first trial. Comparisons between participants who self-selected items vs the groups in which the computer controlled selection also converged on the conclusion of age equivalence in processes underlying item selection.

Adult↗

Aging and individual differences in the development of skilled memory search performance.

We examined individual differences in measures of multiple intellectual abilities and performance on a pure memory search task over 5 experimental sessions. Old (n = 104) and young (n = 97) participants showed expected patterns of substantial improvement in memory search intercepts and slopes in consistently mapped (CM) conditions, relative to varied mapping (VM) conditions. Initial (unskilled) CM and VM memory search was highly correlated with a Semantic Memory Access Speed factor and moderately correlated with General Intelligence. Structural equation models showed that measures of Semantic Memory Access remained a strong predictor of skilled CM search performance in both age groups despite individual differences in CM memory search performance changes. These results indicate qualitative differences in the nature of automaticity between memory search and visual search and suggest age invariance in the mechanisms determining automaticity in memory search.

Adolescent↗

Understanding performance and learning in consistent memory search: an age-related perspective.

This study was conducted to investigate learning in memory search tasks. Young and old participants were trained for 5,640 trials of consistent mapping (CM) and varied mapping (VM) memory search. After training, participants were transferred into New CM and CM Reversal conditions. During training, both young and old adults improved reaction time performance, with more rapid improvement for the young adults. In CM training, both age groups achieved zero comparison slopes, indicating automaticity in CM memory search. VM training maintained a large age-related difference in search times. Age did not moderate the transfer effects, suggesting similar learning mechanisms were responsible for the original CM training gains in both age groups; however, transfer effects were different for CM Reversal and New CM. The pattern of transfer data argues against several possible mechanisms for automaticity in memory search. The data are most compatible with a hypothesis of memory-set unitization as the locus of automaticity in memory search.

Adolescent↗

Stability and accuracy of metamemory in adulthood and aging: a longitudinal analysis.

The stability and accuracy of memory perceptions in 2 longitudinal samples was examined. Sample 1 consisted of 231 adults (22-78 years) tested twice over 2 years. Sample 2 consisted of 234 adults (55-86 years) tested 3 times over 6 years. Measures of perceived and actual memory change were obtained. A primary focus was whether perceptions of memory change stem from application of an implicit theory about aging and memory or from accurate monitoring of actual changes in performance. Individual differences in metamemory were highly stable over time. Results suggested at least some accurate monitoring of memory in Sample 2, in which actual change was greatest. However the overall pattern of results is largely consistent with predictions derived from an implicit theory hypothesis.

Adult↗

Age-related retention of skilled memory search: examination of associative learning, interference, and task-specific skills.

Young and older adults performed skilled memory search after either a 3- or 6-month retention interval. Participants were first trained in consistent-mapping (CM) memory search; then, one of the search conditions was subjected to interfering processing activity prior to the retention interval. Retention testing simultaneously examined situations where interfering processing activity either did or did not intervene between original learning and retention testing. In addition, general task-specific learning was assessed. Results indicate that (a) old and young adults equally retained general, task-specific skills; (b) old adults' performance declined more than young adults' performance for trained CM stimuli; (c) when an interfering processing activity was inserted prior to the retention interval, old adults' performance declined disproportionately more than young adults' performance, especially when compared to the task not subjected to such interference; and (d) for both old and young adults all initial retention deficits were quickly eliminated within retention retraining.

Adolescent↗