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Biomedical subjects

C Huntington

Publications and source records attributed to C Huntington.

9 recordsLinked to original sources

Four new coccidia (Apicomplexia: Eimeriidae) from anoles (Lacertilia: Polychrotidae) in the Dominican Republic.

Fecal samples from 25 Anolis armouri, 2 Anolis bahorucoensis, 48 Anolis cybotes, and 21 Anolis olssoni (Lacertilia: Polychrotidae) from southern Hispaniola were examined for coccidian oocysts. Two eimerians and 2 isosporans are herein described as new species. Sporulated oocysts of Eimeria schwartzi n. sp. from A. armouri are ellipsoidal, 22.7 (20.8-25.0) x 15.7 (14.6-17.7) microns, with spherical to subspherical sporocysts, 7.9 (6.2-9.4) x 7.4 (6.2-8.3) microns. Sporulated oocysts of Isospora reui n. sp. from A. bahorucoensis are spherical to subspherical, 18.2 (15.6-20.0) x 17.8 (15.6-19.8) microns, with ovoid sporocysts, 11.9 (10.4-12.7) x 8.5 (7.5-9.4) microns. Sporulated oocysts of Isospora hendersoni n. sp. from A. armouri and A. cybotes are spherical to subspherical, 23.2 (20.8-26.0) x 21.1 (18.4-23.9) microns, with ellipsoidal sporocysts, 14.7 (12.5-15.6) x 10.0 (9.2-11.4) microns. Sporulated oocysts of Eimeria avilae n. sp. from A. olssoni are cylindrical, 29.3 (26.0-33.3) x 15.9 (13.5-18.9) microns, with ellipsoidal sporocysts 10.2 (9.4-11.4) x 6.8 (5.2-8.0) microns.

Animals↗

A potential animal model for studying CF heterozygote advantage: genetic variation in theophylline-inducible colonic chloride currents among inbred strains of mice.

We have used Ussing chambers to measure chloride secretion by colonic segments (mucosa, muscularis, and serosa) from various inbred strains of mice. We found lower theophylline-induced Cl- secretion in the DBA/2J than in the C57BL/6J strain. Their F1 showed significantly higher levels of Cl- secretion than did the C57BL/6J parental strain while colonic segments from five recombinant inbred B x D lines ranged between the C57BL/6J and F1 values. No major component of the variation appeared to be associated with alleles of the met oncogene region of chromosome 6 or the H-2 region of chromosome 17.

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