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Biomedical subjects

C I Perre

Publications and source records attributed to C I Perre.

11 recordsLinked to original sources

Technetium-99m-sestamibi uptake in axillary lymph node metastases in breast cancer patients.

In a prospective study the value of technetium-99m-sestamibi scintigraphy (MIBI scintigraphy) in staging axillary lymph node involvement in breast cancer patients was established. The study comprised 36 cases. The results of the staging were compared with physical and histological examination. MIBI scintigraphy had a sensitivity of 91% and a total accuracy of 81%. These percentages demonstrate the potential value of this technique; larger series will be needed to confirm our results.

Axilla↗

The value of ultrasound in the evaluation of palpable breast tumours: a prospective study of 400 cases.

In a prospective study, 400 palpable breast tumours were examined to establish the value of ultrasound. 174 Carcinomas were diagnosed by histological examination. The sensitivity of ultrasound examination in detecting malignancy was 96.6%, the specificity 94.2%. Ultrasound examination of a palpable breast tumour is reliable in differentiating between benign and malignant tumours.

Adolescent↗

[Ultrasonographic study of the palpable breast tumor is very useful].

OBJECTIVE: To determine the value of ultrasonographic examination in the assessment of palpable breast tumours, with special reference to the distinction between benign and malignant tumours. DESIGN: Prospective ultrasonographic study; the results of the ultrasonographic examination were compared retrospectively with those of mammographic examination. SETTING: Diakonessenhuis, Utrecht. METHOD: In 282 successive patients, 300 palpable breast tumours were examined ultrasonographically in the period from December 1989 to May 1992 and the findings were compared with those of morbid-anatomical examination (histological examination in solid tumours, cytological examination in cysts). The results of ultrasonographic and mammographic examination of 241 tumours were compared. RESULTS: Of the 300 palpable tumours examined ultrasonographically, 297 were included in the study (122 carcinomas and 175 benign lesions). The sensitivity of ultrasonography was 97.5%, its specificity 92.6%. The predictive value of a positive test result was 90.2%. When the results of ultrasonography and mammography were compared for 204 tumours, the sensitivity of ultrasonography proved to be 97.4% and its specificity 91.0%; for mammography, these figures were 91.3% and 75.3%, respectively. CONCLUSION: Ultrasonography of palpable breast tumours can be a highly reliable diagnostic method, particularly with a view to distinguishing between malignant and benign lesions.

Adolescent↗

[Little extra information with ultrasonic studies of the axillary glands in patients with breast carcinoma].

In order to establish the value of ultrasound examination of the axillary lymph nodes on the presence of lymph node metastases of carcinoma of the breast a prospective survey was carried out in 100 consecutive patients with a carcinoma of the breast on which a lymph node dissection was performed. In the survey the results of the ultrasound examination were compared with the results of the physical and pathological examinations. Although the sensitivity of the ultrasound examination was higher (60%) than that of the physical examination (33%) the ultrasound examination proved insufficiently reliable.

Axilla↗

The non-palpable, radiographically suspicious breast lesion: an analysis of 101 cases.

Analysis of 94 patients with 101 non-palpable, radiographically suspicious, breast lesions revealed 46 malignancies (46%). Comparison of the malignant lesions with 225 palpable carcinomas (221 patients) removed surgically during the same period, showed a higher incidence of carcinoma in situ. Contrary, lymph-node metastases and distant metastases were, at the time of operation, distinctly less than in the patients with non-palpable malignant lesions. A breast-conserving therapy was more often feasible in patients with nonpalpable malignant lesions.

Breast Diseases↗

[Mondor's disease].

Mondor's disease, a harmless superficial thrombophlebitis of mainly thoracic veins, was diagnosed in four patients. Two of them were initially suspected of carcinoma of the breast, while the two others were thought to have a helminthic infection. Symptoms, signs, pathology and aetiology of this disease are discussed.

Adult↗