Biomedical subjects

C I Timon

Publications and source records attributed to C I Timon.

39 records · Page 3Linked to original sources

PubMed1989

Diagnosis, complications, and treatment of malignant otitis externa.

Malignant otitis externa (MOE) is a severe penetrating infection which has spread outside the confines of the external auditory canal to involve temporal bone, mastoid air cells and periaural soft tissues. It is a rare but important condition, having a mortality rate of between 23%-75%. Clinical diagnosis in the early stage is difficult because the symptoms are similar to acute otitis externa. Diabetes Mellitus is an important predisposing factor present in up to 94% of patients. Two cases of MOE are presented underlining the clinical findings, spectrum of activity and treatment of the disease, and stressing the importance of early diagnosis.

Adult↗

PubMedDate not supplied

The accuracy of fine-needle aspiration biopsy in the diagnosis of head and neck masses.

Patients presenting with a mass in the head and neck region require a tissue biopsy in order to make a histological diagnosis. Fine needle aspiration (FNA) offers a safe, well tolerated and inexpensive method of obtaining such a biopsy. When the patient is first seen in the clinic, the FNA can be performed, the result read and appropriate management instituted. The results of FNA biopsies of head and neck masses performed between May 1993 and June 1995, at the Department of Otolaryngology, Head and Neck Surgery in Saint James's Hospital, Dublin were reviewed. Of the 130 patients who had FNA biopsies performed, 78 went on to have surgical excision of the mass. To determine the accuracy of FNA biopsy in the diagnosis of head and neck masses at our unit, we compared the cytology result and the final histology report of these 78 patients. The overall accuracy rate of FNA cytology was 95 per cent, when compared to the final histology result. The accuracy rate was 87 per cent for malignant lesions and 95 per cent for benign lesions. No complications were encountered in this study. Based on our results and those of other studies, we recommended performing FNA in all patients presenting with a mass in the head and neck region.

Adolescent↗

PubMedDate not supplied

Malignant sinonasal tumours: the Dublin Eye and Ear Hospital experience.

We identified 51 patients from pathology and operative records who were treated in the Royal Victoria Eye and Ear Hospital with malignant sinonasal tumours between January 1980 and December 1991. Complete follow up was available in 43 patients. There were 30 males, mean age 50 years, range (10-80) and 13 females, mean age 59 years, range (34-75). Commonest presentations were nasal obstruction, nasal discharge and facial swelling. Patients presented late because of initial non specific symptoms. The maxilla was the site of origin in 18 patients, the ethmoids in 13 patients and the nasal cavity in 12 patients. There was a wide range of histological types with squamous cell carcinoma occurring in 19 patients (44%). All patients were treated with surgery, radiotherapy or a combination of both. Chemotherapy was used as an adjunctive therapy in three patients. Local recurrence occurred in 21 (50%) of the patients. Overall three year survival was 58% and five year survival was 45%. These figures compare favourably with larger series in the literature. A high index of suspicion, early recognition and referral of these patients is required to improve survival.

Adolescent↗