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Biomedical subjects

C Imaoka

Publications and source records attributed to C Imaoka.

At least 19 recordsLinked to original sources
PubMed1995

New markers of remote ischemia in patients with evolving inferior myocardial infarction.

Multivessel disease and decreased left ventricular ejection fraction (LVEF) are believed to be significant predictors of the outcome in patients with acute inferior myocardial infarction (AIMI). We attempted to determine new electrocardiographic (ECG) markers for detecting concomitant left anterior descending (LAD) disease and/or decreased left ventricular function in patients with AIMI. Eighty patients with AIMI were evaluated within 6 h of the onset of symptoms and grouped according to the presence (Group 1) or absence (Group 2) of concomitant LAD disease. All of the patients underwent coronary angiography and left ventriculography 4-6 weeks from the onset of their infarction. We studied the validity of two new ECG markers: S-T depression deeper in lead V5 than in V4 (S-T decreases V5 > V4) and negative U waves (NUs) > 0.5 mm (50 muV) in leads V4-6. The sensitivity and specificity of S-T decreases V5 > V4, NUs in V4-6, or both, in detecting concomitant LAD disease were 56% and 83%, 59% and 87%, and 35% and 98%, respectively. LAD lesions in patients who showed either of these new markers (74% of those with S-T decreases V5 > V4 and 80% of those with NUs in V4-6) were mostly in the proximal segments (AHA segments #6 or #7). Patients with either S-T decreases V5 > V4 or NUs in V4-6 tended to have asynergy in the anterolateral segment, while there was a strong correlation between the asynergy of the anterolateral and septal segments in patients who showed both ECG markers.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1991

Significance of U wave polarities in previous anterior myocardial infarction.

The significance of the polarity of U waves in left precordial leads was evaluated in relation to myocardial perfusion (T1 201 myocardial scintigraphy) and left ventricular function (99m Tc radionuclide ventriculography) in 63 patients with clinical and electrocardiographic evidence of a previous anterior myocardial infarction. Patients were divided into three groups according to the polarity of the U waves: positive U waves, flat U waves, and negative U waves. Twelve matched patients served as normal controls. The following parameters were analyzed: (1) total number of abnormal Q waves; (2) total myocardial perfusion index and regional myocardial perfusion index; (3) global ejection fraction; (4) regional ejection fraction; and (5) number of diseased coronary arteries. The total myocardial perfusion index values were 43.9 +/- 1.0 in controls, 40.8 +/- 3.4 in the positive U wave group, 33.4 +/- 3.5 in the flat U wave group, and 30.3 +/- 4.4 in the patients with negative U waves. Global ejection fractions in these groups were, respectively, 63.9 +/- 8.6%, 65.0 +/- 11.8%, 53.6 +/- 8.1%, and 36.5 +/- 13.6%. The sensitivity of negative U waves suggesting a global ejection fraction of less than 45% was 91.6%, and the specificity was 82.1%. Therefore the size of myocardial infarction increased and left ventricular function decreased, in order, from patients with positive U waves, to those with flat U waves, to those with negative U waves, with statistically significant differences.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1991

Lupus miliaris disseminatus faciei--report of a case in an elderly woman.

A 71-year-old Japanese woman developed red-brown to yellow papules symmetrically on the eyelids and cheeks. The histopathology of a papule showed caseation necrosis surrounded by epitheloid cells intermingled with giant cells in the dermis. The patient was thus diagnosed as lupus miliaris disseminatus faciei (LMDF). To the best of our knowledge, no LMDF patients of such an age have been described previously.

Aged↗
PubMed1990

The significance of U wave polarity in patients with a prior anterior myocardial infarction.

The significance of the polarity of U waves in left precordial leads in patients with a prior anterior myocardial infarction was evaluated in relation to left ventricular function and wall motion by left ventriculography. Ninety-six such patients, with a mean age of 53 years, were divided into three groups according to the polarity of U waves: positive U waves (group P), isoelectric or flat U waves (group F), and negative U waves (group N). The following parameters were analysed: (1) Selvester ECG score; (2) global ejection fraction (EF); (3) regional area change; (4) number of asynergic and akinetic segmental radii; (5) asynergic and akinetic areas. Fifteen patients served as controls. The Selvester ECG scores increased progressively and EF decreased successively with statistically significant differences between groups P, F, and N (P less than 0.01, respectively). The sensitivity of negative U waves for predicting EF of less than 50% was 88.0%, the specificity 81.9%, and the accuracy 84.4%. The incidence of regional area change at the apex of less than 20% was 10.0% in group P, 35.9% in group F, and 74.3% in group N (P less than 0.01). The number of dyssynergic and akinetic radii, and asynergic and akinetic areas increased progressively from group P to F, to N (P less than 0.01). These results demonstrate that the polarity of U waves correlated significantly with left ventricular function and wall motion as well as the size of myocardial infarction. Negative U waves are an important sign of extensive myocardial infarction involving the apex with global ejection fraction of less than 50%. Negative U waves may be associated with lateral ischaemia.

Adult↗
PubMed1990

Proliferating trichilemmal tumor with apocrine sweat glands.

A 43-year-old man with a proliferating trichilemmal tumor is described. Since the tumor had appeared on a pre-existing alopecia and accompanied ectopic apocrine sweat glands, it is supposed that the pathogenesis of the tumor of our patient might be similar to that of an organoid nevus.

Adult↗
PubMed1988

[Statistical survey of malignant skin tumors during the first five years of cases treated at the Dermatological Clinic of Shimane Medical University Hospital].

A statistical survey of malignant skin tumors has been carried out involving the outpatients seen at the Dermatological Clinic of Shimane Medical University Hospital during the period between October, 1979 and October, 1984. Out of 9,702 patients seen, 51 were found to have a malignant skin tumor or, statistically, 0.53% of all patients. The number and type of the malignant skin tumor were as follows: squamous cell carcinoma, 16; basal cell epithelioma, 7; Bowen's disease, 6; Paget's disease, 1; a metastatic carcinoma of the skin, 4; a malignant melanoma, 5; a malignant lymphoma, 10; leukemia, 1 and a multicentric reticulohistiocytoma, 1. reticulohistiocytoma, 1.

Adult↗
PubMed1987

[Evolution of dilated cardiomyopathy from hypertrophic obstructive cardiomyopathy: a case report].

A 20-year-old woman whose echocardiograms showed a rare evolution from hypertrophic to dilated cardiomyopathy during a nine year observation period is described. This patient was initially diagnosed as having hypertrophic obstructive cardiomyopathy (HOCM) at the age of 12 years. Her echocardiogram showed marked thickening of the interventricular septum (IVS) and left ventricular posterior wall (LVPW), asymmetric septal hypertrophy (ASH) and systolic anterior motion of the mitral valve (SAM). Chest radiography revealed a prominent left ventricular border and a cardiothoracic ratio of 0.52. At 18 years of age she experienced onset of palpitation during the 16th week of pregnancy. Her echocardiogram recorded in June 1980 revealed a thickened IVS and LVPW with resolution of the SAM and of the narrow cavity. At 20 years of age she became pregnant again and was admitted to our hospital for the third time at 24 weeks gestation. On admission her blood pressure was 122/60 and her pulse was 56, and moist rales were audible over both lung fields. Peripheral edema was noted. Chest radiography revealed moderate cardiomegaly, a cardiothoracic ratio of 0.66, and congestion of the pulmonary vasculature. An echocardiogram showed thinning of the IVS and LVPW with hypokinesis and dilatation of the cavity compatible with dilated cardiomyopathy (DCM). She delivered a boy on July 15th 1982 at 32 weeks gestation following which she developed marked congestive heart failure. She expired one month later. A chest radiograph made one day before death revealed marked cardiomegaly, a cardiothoracic ratio of 0.76, prominent pulmonary vasculature and a pleural effusion. Autopsy was refused; therefore the terminal DCM-like features were not clarified pathologically. However, the slow progression from HOCM to HCM during eight years and then rapid progression from HCM to DCM during four months was most impressive.

Adult↗
PubMed1986

A case of normotensive pheochromocytoma masquerading as a dilated cardiomyopathy.

A case of right adrenal pheochromocytoma masquerading as a dilated cardiomyopathy is described. This patient was normotensive throughout 8 years of observation. Hyperglycemia and an abnormal glucose tolerance test were a clue to the diagnosis which was confirmed by the findings of increased plasma and urinary epinephrine and norepinephrine values. In patients with dilated cardiomyopathy the possibility of a pheochromocytoma should be considered.

Adrenal Gland Neoplasms↗
PubMed1986

[Pheochromocytoma with normal blood pressure and dilated cardiomyopathy: a case report].

A rare complication of normotensive pheochromocytoma with dilated cardiomyopathy is described. This 57-year-old man first experienced palpitation eight years ago when his blood pressure, electrocardiogram and chest radiograph were all within normal limits. Five years later he was admitted to another hospital because of palpitation and was diagnosed as having dilated cardiomyopathy on the basis of cardiac catheterization and cardiac muscle biopsy. In December, 1984, he was admitted to our hospital for treatment of congestive heart failure. On admission, his electrocardiogram revealed left atrial overloading, left axis deviation, left ventricular hypertrophy with intraventricular conduction disturbances and frequent premature ventricular contractions. Echocardiography revealed marked biventricular dilatation with severe hypokinesis of the interventricular septum and the posterior wall of the left ventricle, and a B-B' step of the anterior mitral leaflet. Fasting blood sugar was slightly elevated and a 75 g glucose tolerance test was abnormal. An abdominal echogram and abdominal CT revealed a 67 mm diameter mass immediately superior to the right kidney. Blood and urine catecholamine levels were significantly increased. He was diagnosed as having a pheochromocytoma. Interestingly, he had been normotensive during the eight years until his fatal outcome. He died of congestive heart failure. Needle necropsy findings of the adrenal revealed pheochromocytoma, and those of the cardiac muscle revealed enlarged muscle cells and mild fibrosis.

Adrenal Gland Neoplasms↗