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C J Baker

Publications and source records attributed to C J Baker.

275 records · Page 16Linked to original sources
PubMedDate not supplied

Increased risk of group B streptococcal disease in twins.

Infants who are the product of multiple births comprise a newly defined group of patients at increased risk for the development of invasive, group B streptococcal infection. This report summarizes the clinical and bacteriological features of 11 sets of twins and one set of triplets in which one (nine sets) or more (three sets) infants had proved early- or late-onset group B streptococcal infection. Reasons for the enhanced susceptability of index patients and their siblings are discussed. On the basis of these observations, an emperical approach is proposed for the treatment of the apparently noninvolved sibling of a twin with invasive group B streptococcal infection.

Antibodies, Bacterial↗
PubMedDate not supplied

Fibronectin levels in premature infants with late-onset sepsis.

Physical features do not reliably distinguish premature infants with bacterial infections from those with noninfectious conditions. We evaluated the association of depressed plasma fibronectin with sepsis among hospitalized very low birth weight infants (< 1500 gm). Reference values were determined by sequential plasma sampling from 60 healthy very low birth weight infants. Among 17 very low birth weight infants with proved late-onset sepsis (mean age, 20 days; range, 10 to 42 days), 9 had plasma fibronectin levels more than 1 SD below the age- and birth weight-associated mean. Overall, the sensitivity and specificity of the finding of depressed fibronectin levels were 53% and 94%, respectively. These data suggest that depression of plasma fibronectin occurs commonly in association with late-onset sepsis among hospitalized premature infants.

Bacteremia↗