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Biomedical subjects

C J Foy

Publications and source records attributed to C J Foy.

24 records · Page 2Linked to original sources
PubMed1989

HIV infection and Scottish general practice: knowledge and attitudes.

To assess the knowledge and attitudes of general practitioners about HIV infection, a postal survey was undertaken of one in three of all principals in Scotland; 834 (77.6%) responded. Respondents' knowledge about HIV was often limited, and they found the discussion of sexual behaviour difficult. Most were in favour of routine HIV testing being offered to patients, but against testing without consent. Most general practitioners considered consent unnecessary for the passing of information about HIV status between medical colleagues, but necessary for informing others, in particular the patient's family and sexual partners. Most general practitioners would accept high-risk and HIV-positive patients onto their lists but less than half would accept intravenous drug users. Most respondents did not feel at significant personal risk of HIV infection, but expressed reservations about many other aspects of HIV infection in general practice. If practitioners are to fulfil their potential for tackling the problems of HIV infection, they need increased resources and a policy for education and training that is responsive to local needs.

Acquired Immunodeficiency Syndrome↗
PubMed1985

Dietary sodium and arterial blood pressure: evidence against genetic susceptibility.

Thirty five subjects with both parents in the top third of their age specific blood pressure distributions and 31 subjects with both parents in the bottom third of their blood pressure distributions restricted their intake of sodium for eight weeks while taking part in a double blind, randomised crossover trial of supplements of sodium and placebo. A comparison of two periods of four weeks at different intakes of sodium showed no differences in blood pressure in either the groups as a whole or the subgroups who complied best with the diet and tablets. In the compliant subgroups mean urinary sodium excretions were above 120 mmol(mEq) and below 50 mmol/day. The study provides evidence against the hypothesis that people with a family history of high blood pressure are more susceptible in their blood pressure response to dietary sodium.

Adult↗
PubMed1983

Comparison of blood pressure, sodium intake, and other variables in offspring with and without a family history of high blood pressure.

The blood pressure, body weight, mean 24 hour urinary electrolyte excretion, and plasma renin activity in offspring whose parents both belonged to the top third of the distribution of blood pressure in their 5-year age-group were compared with those in offspring whose parents belonged to the bottom third. Altogether 116 offspring, aged 10-43 years, took part in the study. Systolic pressure was higher in the offspring with a family history of high blood pressure, but there was no difference in 24-h urinary electrolyte excretion or plasma renin activity. The study had a power of over 80% to detect a 20 mmol difference in sodium excretion, and it provides evidence against the hypothesis that hypertensives have an avidity for sodium.

Adolescent↗
PubMed1983

Dietary sodium restriction for mild hypertension in general practice.

Eighteen patients with stable mild hypertension (mean blood pressure 144/93 mm Hg) restricted their sodium intake for eight weeks while taking part in a double blind randomised crossover trial of slow sodium and placebo tablets. Mean 24 hour urinary sodium excretion was 143 mmol(mEq) during the period on slow sodium and 87 mmol during the period on placebo. Five patients were unable to reduce their sodium intake below 120 mmol, but the others had a mean 24 hour urinary sodium excretion of 59 mmol during the period on placebo. There was no significant difference in blood pressure between the slow sodium and placebo treatment periods, although the study had a power of 99% to detect a difference of 5 mm Hg in mean arterial pressure between the two periods. Moderate dietary sodium restriction does not lower blood pressure in patients with this degree of hypertension.

Adult↗
PubMed1982

Dietary sodium and arterial pressure: problems of studies within a single population.

The nature of the relationship between dietary sodium and arterial pressure remains uncertain, largely because of the difficulty of investigating this relationship within a single population. There are two main hypotheses: one requires that hypertensive and normotensive patients differ in their sodium intake, the other that they differ in their susceptibility to dietary sodium. Neither hypothesis has been fully explored. In this paper the types of study required to test each hypothesis are considered and published work is used to illustrate the problems of interpreting studies in this field.

Adolescent↗