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Biomedical subjects

C J Hansen

Publications and source records attributed to C J Hansen.

27 records · Page 2Linked to original sources

Residents' leadership styles and effectiveness as perceived by nurses.

Although physicians are required to act as leaders in a variety of situations, leadership ability and leadership training have been largely ignored by medical educators. The leadership styles and leadership effectiveness of 17 residents in a community hospital were studied as part of a leadership training seminar. Self-ratings and ratings of the residents by nurses who had worked with them were used to assess the residents' leadership style and the nurses' perceptions of the effectiveness of those styles. Styles that emphasized relationships with co-workers (encouraging and coaching styles) predominated over low relationship-oriented styles (delegating and structuring). The nurses perceived individual residents who exhibited encouraging and coaching leadership styles as being distinctly more effective leaders than the residents who exhibited structuring and delegating styles. The residents, however, rated all four styles as similarly effective. Leadership training programs and studies of the type reported here may provide an opportunity for faculty members to help residents learn more appropriate and productive styles of leadership.

Female↗

Physicians' opinions of the accuracy, accessibility, and frequency of use of ten sources of new drug information.

We surveyed internists, surgeons, and general practitioners in a six-county area of North Carolina to determine how accurate and accessible they believed ten sources of new drug information to be and how frequently they used each of the sources. Evaluable questionnaires were returned by 119 of the 336 physicians. The majority indicated that all sources were accessible. Commercial sources were thought to be less accurate than noncommercial sources, but were used more frequently (P less than .0002), especially by physicians who had practiced more than 15 years (P less than .02). Written sources were thought to be more accurate (P less than .0001) and were preferred over oral sources of new drug information (P less than .0004). Pharmacists and pharmacology textbooks were believed to be both accurate and accessible, but were relatively infrequently used.

Adult↗

Alternative RNA splicing generates transcripts encoding a thorax-specific isoform of Drosophila melanogaster myosin heavy chain.

Genomic and cDNA sequencing studies show that transcripts from the muscle myosin heavy-chain (MHC) gene of Drosophila melanogaster are alternatively spliced, producing RNAs that encode at least two MHC isoforms with different C termini. Transcripts encoding an MHC isoform with 27 unique C-terminal amino acids accumulate during both larval and adult muscle differentiation. Transcripts for the second isoform encode one unique C-terminal amino acid and accumulate almost exclusively in pupal and adult thoracic segments, the location of the indirect flight muscles. The 3' splice acceptor site preceding the thorax-specific exon is unusually purine rich and thus may serve as a thorax-specific splicing signal. We suggest that the alternative C termini of these two MHC isoforms control myofilament assembly and may play a role in generating the distinctive myofilament organizations of flight muscle and other muscle types.

Amino Acid Sequence↗

Factors that predict improvement in left ventricular ejection fraction after coronary angioplasty for acute myocardial infarction.

Acute and follow-up angiograms were analyzed in 75 patients with acute myocardial infarction treated with emergency coronary angioplasty to determine factors that might predict improvement in left ventricular ejection fraction. Ejection fraction improved 8.4 +/- 8.2% in 60 patients who maintained patent infarct vessels at follow-up angiography, compared with -4.1 +/- 6.0% in 15 patients who developed reocclusion (p less than .001). In patients with patent infarct vessels, univariate analysis revealed the following significant predictors of improvement in ejection fraction: initial ejection fraction (r = -.38, p less than .003) subtotal vs total stenosis (12.9 +/- 9.3% vs 6.9 +/- 7.3%, p less than .02), infarct vessel (left anterior descending 11.0 +/- 8.4%, right 6.8 +/- 6.4%, circumflex 2.6 +/- 7.5%, p less than .02), and time to follow-up study (less than or equal to 15 days vs greater than 15 days) (4.8 +/- 5.8% vs 9.8 +/- 8.6%, p less than .03). Reperfusion time (less than or equal to 2 hr vs greater than 2 hr) predicted improvement when subtotal stenoses and stuttering infarctions were excluded (10.6 +/- 7.0% vs 4.9 +/- 6.9, p less than .03). Multivariate analysis showed initial ejection fraction and subtotal vs total stenosis to be independent predictors. Patients with anterior infarctions, low initial ejection fractions, and subtotal stenoses or reperfusion times less than or equal to 2 hr are likely to benefit most from coronary angioplasty for acute myocardial infarction.

Angioplasty, Balloon↗

Clinical usage of the leukocyte count in emergency room decision making.

Leukocyte (WBC) and differential counts are commonly used, but their clinical characteristics are poorly understood. To understand how the clinician interprets the WBC count in the presence of these uncertainties, the authors used a case vignette with a questionnaire to isolate physician reaction to an abnormal WBC count as compared with a normal control WBC count. In response to a case vignette of a urinary tract infection in the emergency room, physicians altered their diagnostic and therapeutic plans based solely on the WBC count. The results of the study also suggest that the cost of the WBC is not limited to the test cost, but also includes the cost of the physician reaction to the abnormal WBC count.

Attitude of Health Personnel↗