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Biomedical subjects

C J Moniz

Publications and source records attributed to C J Moniz.

3 recordsLinked to original sources

Meperidine: second-line agent with first-line prescribing practices.

Results from this survey need to be viewed within the context of the small number of responses (20%), which may not fully represent the knowledge base of all house officers. Recommendations established by the Agency for Health Care Policy and Research (AHCPR) define standards of care for acute and chronic pain management and address many of the problems seen nationally with meperidine and its metabolite, normeperidine. Data from this survey have assisted us in providing educational programs which are in line with these guidelines for house officers.

Analgesics, Opioid↗

Long-term effects of the menopause and sex hormones on skin thickness.

Skin collagen content and skin thickness in a group of postmenopausal women who had been treated with sex hormone implants were compared with those in an untreated group of similar women. Both skin collagen content and thickness were found to be significantly greater in the treated than in the untreated group. In the untreated women skin collagen content declined in relation to menopausal age but not to chronological age. No correlation was found with menopausal age, chronological age or duration of therapy in the treated group. These data suggest that skin collagen is influenced by the sex hormone status and declines after the menopause, contributing to the increase in urinary hydroxyproline excretion that has been reported to occur at this time.

Collagen↗