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Biomedical subjects

C J Njiokiktjien

Publications and source records attributed to C J Njiokiktjien.

10 recordsLinked to original sources
PubMed1994

Interhemispheric interaction in children of 7-8: analysis of EEG coherence and finger tapping parameters.

To investigate interhemispheric interaction (IHI), the EEGs of 42 children between the ages of 7-8 years were recorded while they were performing, as fast as possible, both unimanual and bimanual rhythmic tapping tasks. As an EEG index of IHI we used coherence values (Coh) in the alpha band in the pairs of leads F3/F4, C3/C4, P3/P4, O1/O2, and T3/T4 during resting and tapping. The difference between left hand (L-L) and right hand (R-R) intertap intervals in comparable conditions was though to reflect IHI. Interhemispheric alpha Coh increase was only evident in bimanual rhythmic tasks, and was confined to the C3/C4 and P3/P4 regions. Coh in these brain areas correlated negatively with the time difference between the L-L and R-R intertap intervals. The results show that interhemispheric alpha Coh. can be regarded as an index of IHI during bimanual tapping, and support the clinical hypothesis that bimanual versus unimanual tapping might reflect interhemispheric or callosal function.

Alpha Rhythm↗
PubMed1982

Neurological condition at birth in relation to the electroencephalogram (EEG) and visual evoked potential (VEP) at the age of 5.

The correlation between the neonatal neurological condition (Prechtl) and VEP and EEG parameters at the age of 5 have been investigated in 87 normal children. It was found that the more optimal the neurological condition at birth, the shorter the VEP peak latencies (especially of the late components) at the age of 5. Only few and weak correlations between the neonatal condition and EEG at the age of 5 were found. The VEP appears to be a more sensitive detector for late sequelae of supposed perinatal neurological problems than EEG. VEP changes can be explained by "inattention' or "distraction'. Another factor may be delayed maturation.

Age Factors↗
PubMed1980

Subdural hygroma: results of treatment by ventriculo-abdominal shunt.

Subdural hygromas, which differ from acute and chronic subdural haematomas in clinical features and pathogenetic mechanism, can occur as isolated lesions or in association with ventricular dilatation and/or subarachnoid cysts which are mistaken for atrophy. On the basis of the postulate that these fluid accumulations might be related to a disturbance in CSF circulation, we treated them by ventriculoperitoneal CSF drainage. This was regarded as indicated only for children with symptoms of retardation and a distended ventricular system. Disappearance of the hygroma or the cortical cysts and ventricular dilatation was demonstrated in 9 of 14 children treated by ventriculo-abdominal shunt and in 4 of 7 less seriously affected untreated children. Clinical improvement came later than neuroradiological improvement, and was incomplete in a number of children. Although there are anamnestic factors with an unfavourable effect on development, the hygromas per se can cause cerebral dysfunction which is associated with their bifrontal localization. The principal symptoms are those of retardation in the development of verbal expression, leg motor function and manipulation.

Arachnoid↗
PubMed1977

EEG and visual evoked responses in children with learning disorders.

A study was made of 58 children with learning disorders, in all of whom a spontaneous EEG as well as a Visual Evoked Response (VER) was registered. The latencies in the secondary complex of the VER were increased and the amplitudes of waves II and III were increased as compared with normal subjects. Two subgroups--children with a good and children with a poor clinical test score--did not differ in VER parameters. A spontaneous EEG evaluated as abnormal was present in 45% of the children. These children showed more absence of peaks in both VER complexes and more increased latencies in the primary complex than children with a normal EEG. The findings show that the VER is a valuable supplement to EEG in demonstrating organic changes in children with learning disorders.

Adult↗