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Biomedical subjects

C J Ogborn

Publications and source records attributed to C J Ogborn.

5 recordsLinked to original sources
PubMed1999

Ipratropium bromide added to asthma treatment in the pediatric emergency department.

OBJECTIVE: To determine if the addition of ipratropium bromide to the emergency department (ED) treatment of childhood asthma reduces time to discharge, number of nebulizer treatments before discharge, and the rate of hospitalization. METHODS: Patients >12 months of age were eligible if they were to be treated according to a standardized ED protocol for acute asthma with nebulized albuterol (2.5 mg/dose if weight <30 kg, otherwise 5 mg/dose) and oral prednisone or prednisolone (2 mg/kg up to 80 mg). Subjects were randomized to receive either ipratropium (250 microg/dose) or normal saline (1 mL/dose) with each of the first three nebulized albuterol doses. Further treatment after the first hour was determined by physicians blinded to subject group assignment. Records were reviewed to determine the length of time to discharge home from the ED, number of doses of albuterol given before discharge, and the number of patients admitted to the hospital. RESULTS: Four hundred twenty-seven patients were randomized to ipratropium or control groups; these groups were similar in all baseline measures. Among patients discharged from the ED, ipratropium group subjects had 13% shorter treatment time (mean, 185 minutes, vs control, 213 minutes) and fewer total albuterol doses (median, three, vs control, four). Admission rates did not differ significantly (18%, vs control, 22%). CONCLUSIONS: The addition of three doses of ipratropium to an ED treatment protocol for acute asthma was associated with reductions in duration and amount of treatment before discharge.

Administration, Inhalation↗
PubMed1994

Urinary cotinine as a measure of passive smoke exposure in asthmatic children.

This study sought to determine (1) the association between passive smoke exposure and acute symptoms in asthmatic children and (2) the association between parental report and objective measures of passive smoke exposure. Asthmatic children ages 3 to 11 were eligible for the study, which involved measurement of smoke exposure by questionnaire and by urine sample at a time of an acute asthma attack and then later when the child was symptom-free. High levels of passive smoke exposure were detected at both times in most children. Parental report of passive smoke exposure correlated with urinary measure of exposure.

Acute Disease↗
PubMed1994

Childhood injury and emergency medical services for children.

Injury is the leading cause of death in children in the United States, and it is a leading reason for children to need emergent medical attention. The care of injured and ill children can best be coordinated through a comprehensive system of Emergency Medical Services for Children (EMS-C). This article reviews childhood injury epidemiology, details the history and components of EMS-C systems, and discusses areas for improvement of and individual involvement in EMS-C.

Adolescent↗