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Biomedical subjects

C J Poole

Publications and source records attributed to C J Poole.

9 recordsLinked to original sources
PubMed1992

Effects of a change in shift work on health.

Aspects of health were studied in a sample of factory workers who changed their pattern of working from 'fortnight about' to three advancing shifts. Within the same factory and doing similar work there was a comparison group who were working permanent days only. The change in shifts was associated with more difficulty with sleep, more indigestion, higher alcohol consumption, reduced alertness and a worse social life. There was more minor psychiatric disturbance in those who worked three shifts than in those who worked days only.

Absenteeism↗
PubMed1992

Control of diabetes mellitus in shift workers.

OBJECTIVE: To determine whether the control of diabetes is different in insulin treated diabetic subjects who work shifts compared with those who do not work shifts and whether control is related to the type of shift worked. DESIGN: Prospective controlled study of 32 diabetic subjects working either regular days or shifts in a large car assembly factory. Insulin treated subjects who underwent a change in their pattern of shift work had diabetic control assessed before and six months after a change in shifts. MAIN OUTCOME MEASURES: Random plasma glucose, serum fructosamine, and haemoglobin A1 while at work. RESULTS: Diabetic control of insulin treated subjects who worked shifts was not significantly different from insulin treated subjects who worked days only. Diabetic control was poor in both groups and similar to that of diabetic subjects treated with oral hypoglycaemic agents. In those subjects that moved to a more rapidly rotating shift pattern there was a significant deterioration in control (serum fructosamine concentration before, 405 (SD 68); after, 481 (SD 90) mumol/l, p less than 0.01). CONCLUSIONS: The control of diabetes in insulin treated diabetic subjects who worked shifts was no worse than those who worked days only. Slowly rotating shifts were associated with better diabetic control than more rapidly rotating shifts.

Blood Glucose↗
PubMed1990

Fusion of Rous-sarcoma-virus-transformed rat cells to morphologically normal human or rat cells results in transcriptional suppression of the provirus that depends on its chromosomal integration site.

The fusion of a Rous sarcoma virus (RSV)-transformed rat fibroblast clone to at least 2 different human cell types reproducibly produces phenotypically normal hybrids. Analysis of such hybrids reveals that proviral silence is the result of transcriptional down-regulation, presumably by a trans-acting human molecule. Furthermore, this phenomenon seems to be strongly influenced by the proviral chromosomal integration site and its imposition may entail a mechanism that is required only transiently.

Animals↗
PubMedDate not supplied

Neonatal circumcision.

The American Academy of Pediatrics has stated that there is no valid medical reason for performing routine neonatal circumcision. Although the issue is hotly debated in medical circles, little attention has been given to the issue in the nursing literature. It is important that nurses understand the medical, social, religious, and child care issues involved in order to help parents make informed decisions regarding circumcision of their neonate.

Africa↗