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Biomedical subjects

C J Randall

Publications and source records attributed to C J Randall.

At least 37 records · Page 2Linked to original sources
PubMed1987

Advanced laryngeal cancer: a management perspective.

A retrospective study of 197 T3 and T4 squamous cell carcinomas of the larynx presenting between 1969 and 1978 has been undertaken. These patients have in the main been treated by primary radiotherapy with back-up salvage surgery. The aim of the study was to examine survival, and to try to identify reasons for failure of control. Various prognostic factors have been analysed and are discussed. Overall 5-year survival was 53 per cent but patients with nodal disease responded poorly. Subglottic tumours have a better survival than usually reported. Failure to pick up recurrence was the main problem, and in particular a persistently fixed cord carried a very poor prognosis if laryngectomy was delayed.

Aged↗
PubMed1987

Marginal mandibulectomy for malignant disease: indications, rationale, and results.

The theoretical basis for performing marginal mandibular resection, as opposed to segmental resection, is discussed; and criteria are suggested. Results are presented that suggest that, in the treatment of malignant disease around the jaw, although the mortality from other tobacco- and alcohol-related diseases remains high, good functional and cosmetic results can be achieved with no loss of local control.

Humans↗
PubMed1987

Observations on femoral head abnormalities in broilers.

Detachment of the proximal femoral cartilaginous epiphysis was observed in broilers that were being down-graded at slaughter as a result of haemorrhage into thigh musculature. A traumatic aetiology is proposed with injury occurring at catching. Examination of field case material, and birds culled from a commercial flock of the same strain, revealed that physeal lesions are not infrequent in proximal femora. Clefts and areas of matrix necrosis occurred in normal and dyschondroplastic physeal cartilage. Clefts were thought to result from repetitive minor trauma insufficient to cause total detachment of the cartilaginous epiphysis. Total detachment may result from an acute traumatic episode or be a consequence of pre-existing physeal lesions. A traumatic aetiology suggests that in such cases the terms fracture separation or traumatic epiphyseolysis of the cartilaginous epiphysis are more appropriate than femoral head necrosis or degeneration.

Animals↗
PubMed1986

Malignant tumours of the tongue in young adults. Experience of a secondary referral centre.

Twenty-three cases of malignant tongue tumours in patients aged 15 to 30 are reported. Treatment and prognosis in the 18 for which follow-up information is available are discussed. The disease appears to be very similar to that in older subjects except for a greater incidence of neck node metastases. Close follow-up after primary treatment is essential since there is a high possibility of recurrent disease but which may respond well to salvage surgery if identified early. A greater awareness of the occurrence of tongue cancer in young adults is also necessary.

Adolescent↗
PubMed1986

Tendon lesions in broiler fowls.

Tendon lesions have been studied in 35 broiler or broiler breeder fowls. Tendon rupture most commonly affected the gastrocnemius and flexor muscles but was also seen in cranial tibial muscles (four cases) and the patellar tendon (one case). In nine birds tenosynovitis, characterised by a marked inflammatory response, was identified. In others, however, rupture occurred without appreciable inflammation and these cases were concluded to be comparable to spontaneous tendon rupture in other species. A traumatic aetiology is suggested in these cases, as other pelvic limb tendons or ligament rupture was a frequent concomitant finding. Degenerative tendon lesions were present but it is uncertain whether such changes are primary or secondary to rupture.

Animals↗
PubMed1984

Quinsy following tonsillectomy (five case reports).

Five cases of post-tonsillectomy quinsy are presented, usually associated with tonsillar remnants. Four of these had no pus and one did, but the clinical picture was the same. Hence, if tonsillectomy is performed to prevent further quinsies, it must be careful and complete.

Adult↗
PubMed1984

Nasal septal chondrosarcoma (a long-term follow-up report).

A case of nasal septal chondrosarcoma is presented which, after radical surgery, recurred after seven and a half years. The post-mortem findings showed gross local spread and dural seedlings. The clinical implications are discussed and the literature reviewed.

Chondrosarcoma↗