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Biomedical subjects

C J Tegtmeyer

Publications and source records attributed to C J Tegtmeyer.

At least 73 records · Page 4Linked to original sources
PubMed1980

Percutaneous transluminal dilatation of the renal arteries: techniques and results.

The techniques and results of percutaneous transluminal angioplasty (TPA) of the renal arteries were evaluated in 20 hypertensive patients with 25 renal artery stenoses. Follow-up angiograms have been obtained in nine patients. Many patients had evidence of both essential and angiotensinogenic hypertension. Eleven patients had evidence of severe diffuse atherosclerotic disease, and nine patients had evidence of renal insufficiency. The mean systolic pressures before and after PTA were 203.80 and 150.30, respectively. The mean diastolic pressures before and after PTA were 117.45 and 85.95, respectively. Ten patients were cured. Six patients with long histories of hypertension and a recent increase in blood pressure were classified as having blood pressure easier to control with antihypertensive medication following PTA. Three patients failed to respond to PTA, and one patient was a technical failure. The advantages of this technique include avoidance of general anesthesia and a major surgical procedure, decreased cost, and a shortened hospital stay. The technique can be easily repeated if necessary, and future surgical intervention is not precluded if the method is unsuccessful.

Adult↗
PubMed1980

The axillary approach to percutaneous renal artery dilatation.

The axillary approach to percutaneous transluminal angioplasty of the renal arteries is described. This technique simplifies renal dilatation in patients with severe atherosclerotic disease in the vessels distal to the renal arteries.

Arteriosclerosis↗
PubMed1979

Crohn's disease associated with Takayasu's arteritis.

In a young woman with Takayasu's arteritis, standard roentgenographic studies suggested a diagnosis of Crohn's ileocolitis. Mesenteric angiography was performed and revealed specific abnormalities diagnostic of Crohn's disease, namely, the zoning sign in the cecum with a hypervascular inner layer and a hypovascular outer layer, and paraintestinal inflammatory neovasculature adjacent to the ascending colon. In addition, several helpful but nonspecific findings were demonstrated, and these features are reviewed. This patient represents another example of large vessel lesions associated with inflammatory bowel disease.

Adult↗
PubMed1979

Identification and differentiation of surgically correctable hypertension due to primary aldosteronism.

During a protocol study for the evaluation of patients with primary aldosteronism, a variety of diagnostic studies were employed in an attempt to identify patients with primary aldosteronism and to differentiate patients with adrenal adenoma from patients with idiopathic adrenal hyperplasia. In this study, we are able to demonstrate the utility of (1) absent postural increase in plasma aldosterone concentration, (2) adrenal scanning and (3) normalization of blood pressure with spironolactone therapy in identifying patients with primary aldosterone excess who have an adrenal adenoma, surgical removal of which results in eliminating their hypertension.

Adenoma↗
PubMed1979

Arthrography of the knee: a comparative study of the accuracy of single and double contrast techniques.

Single and double contrast arthrographic techniques were compared in 951 patinets with suspected meniscal injuries. Exploratory surgery of the knee was performed in 384 of these patients and good clinical follow-up was obtained in 135 patients. In the latter two groups of patients, the single contrast technique was 97% accurate in assessing the medial meniscus and 96% accurate in assessing the lateral meniscus. Double contrast arthrography was 97% accurate in assessing the medial meniscus and 93% accurate in assessing the lateral meniscus. Numerical differences in the results from the two techniques were not statistically significant. Therefore both techniques can be considered equally effective diagnostically.

Adolescent↗
PubMed1978

Staging laparotomy in Hodgkin's disease.

Staging laparotomy was performed at the University of Virginia Medical Center on 111 patients with Hodgkin's disease. The operation included multiple liver and lymph node biopsies and, excepting three patients, splenectomy. The histopathology was reviewed and the 111 patients were classified as follows: nodular sclerosis, 74; mixed cellularity, 28; lymphocyte predominance, 7; and undetermined, 2. There were no deaths. Wound, pulmonary or urinary tract complications occurred in 11 patients. One case of postoperative thrombophlebitis occurred and in another case small bowel obstruction developed, and resolved without reoperation. The pathologic stage (PS) following laparotomy was unchanged from the clinical stage (CS) in 64%, reduced in 20%, and advanced in 16%. The therapy, however, was altered in 38% of the patients. Lymphangiography in 103 patients was interpreted as showing lymph node involvement in 38, equivocal involvement in 11, and no involvement in 54. Among the 92 examinations reported as either positive or negative, 77% were confirmed histopathologically, 21% were falsely positive, and 2% were falsely negative. The spleen was positive for Hodgkin's disease in 39% of cases, and in these patients with positive spleens there was no reason to suspect intra-abdominal involvement preoperatively in 21%.

Abdominal Neoplasms↗
PubMed1978

Angiographic diagnosis of renal tumors associated with polycystic disease.

Two cases of renal cell carcinoma associated with polycystic disease of the kidney are presented. The literature is reviewed and the angiographic findings are discussed. These cases suggest that angiography is necessary to make the diagnosis of renal tumors associated with renal polycystic disease.

Adenocarcinoma↗
PubMed1978

A prospective study of plasma DNA in the diagnosis of pulmonary embolism.

To assess the usefulness of plasma deoxyribonucleic acid (DNA) detection in the diagnosis of pulmonary embolism (PE), we prospectively studied the frequency and duration of the occurrence of free plasma DNA in 23 patients with PE and in 49 patients with pneumonia, myocardial infarction, thrombophlebitis, or normal lung scans. Plasma DNA was detected in 19 of the 23 patients (83 per cent) with PE and in none of the 49 patients with other diagnoses. Eighteen of the 19 PE patients with free DNA had persistence of DNA on all subsequent sampling for up to 5 days. In this series, plasma DNA had a sensitivity of 83 per cent in the diagnosis of PE and was extremely specific for PE. Thus, detection of free plasma DNA may be useful as a rapid, noninvasive test to aid in the diagnois of PE.

DNA↗
PubMed1977

Nephroblastoma with right atrial extension: preoperative diagnosis and management.

A 14-year-old black boy, with a large nephroblastoma of the right kidney, had preoperative identification of inferior vena cava and right atrial involvement. Renal arteriography revealed linear arterial channels in the anatomic distribution of the inferior vena cava and venography revealed total caval occlusion and a right atrial mass. Radical excision, using a cardiopulmonary bypass, resulted in a 6-month postoperative survival.

Adolescent↗
PubMed1977

Roentgenographic assessment of causes of cardiac pacemaker failure and complications.

Implantation of a permanent pacemaker to stimulate the heart is a well established procedure of great benefit. However, a malfunctioning pacemaker is a hazard to well-bing and to life. Once a pacemaker has been installed the physician's attention is directed not only to the patient's illness but also the unique complications of cardiac pacemakers. Roentgenograms are a valuable resource in the assessment of patients with pacemakers. It is essential that the radiologist thorougly understand the extent to which radiologic studies can depict the functioning of the complications associated with pacemakers. The roentgenographic assessment of the causes of pacemaker failure and the complications associated with permanent pacemakers are reviewed and the role of the roentgenogram is defined.

Bronchial Fistula↗
PubMed1977

Axillary, subclavian, and brachiocephalic vein obstruction.

The consequences of occlusion of a major upper extremity vein were evaluated in eight patients with effort thrombosis, ten with thrombosis secondary to intimal injury, six with extrinsic compression, and one hypercoagulable patient, all of whom were followed for an average of 4 years. Twenty-two patients had venography, which confirmed the diagnosis but often failed to define the proximal extent of obstruction. Thirteen patients had noninvasive hemodynamic studies which did not corroborate chronic morbidity, but which were valuable in assessing the effect os specific therapy. Twelve patients were treated with anticoagulants, and six had operative removal or bypass of the obstruction. Three patients had pulmonary emboli; two embolized while on anticoagulants and both died. Swelling, pain, prominent veins, and easy fatigability of the affected extremity were the late sequelae of occlusion. Chronic morbidity was more dependent on etiology than on initial treatment. Thrombosis secondary to intimal injury caused no persistent symptoms, whether treated with anticoagulants or not. Effort thrombosis was intermediate: three fourths complained that their affected arm tired easily and half had prominent veins or persistent swelling. All of those with obstruction secondary to extrinsic compression had easy fatigability. The majority also had concomitant swelling, pain, and prominent collaterals. Operative treatment produced objective improvement in venous outflow but often was unsuccessful in relieving symptoms, particularly in patients with obstruction from extrinsic compression.

Adolescent↗