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Biomedical subjects

C J Weng

Publications and source records attributed to C J Weng.

15 recordsLinked to original sources
PubMed2001

Breast reconstruction with TRAM flap after subcutaneous mastectomy for injected material (siliconoma).

Many patients throughout the world have had breast augmentation using injectable materials. In the Far East, an adulterated impure silicone has been used by non-medical persons and unlicensed 'cosmetic surgeons' as well as by licensed physicians. The injected material usually causes a granulomatous reaction, tenderness, erythema, pain or discomfort and even skin necrosis. Eventually, the injected breast becomes very hard and develops a distorted contour. Previous treatment was by subcutaneous mastectomy with immediate or delayed reconstruction using a silicone prosthesis. The results of this were often unsatisfactory. We obtained more satisfactory results in 11 patients who had the siliconoma removed by subcutaneous mastectomy and the breast reconstructed with a de-epithelialised TRAM flap.

Adult↗
PubMed1999

Breast reconstruction following excision of phylloides tumor.

There are few papers published on breast reconstruction after excision of phylloides tumor. Six patients who had reconstruction of the breast following excision of phylloides tumor are described. All underwent wide excision or subcutaneous mastectomy followed by immediate or delayed reconstruction with implants or autologous tissue. The mean follow-up was 5 years (range, 2.5-7 years). One patient died of metastases; the others survived without evidence of recurrence. The etiology, incidence, diagnosis, and treatment of these tumors are discussed. The aesthetic results in these patients is also described.

Adolescent↗
PubMed1998

Surgical reconstruction in cryptophthalmos.

Cryptophthalmos is the congenital absence of the eyelid with skin passing continuously from the forehead onto the cheek over a malformed eye. The deformity can be classified into three types: complete, incomplete and abortive. We present the cases of two siblings, each with incomplete cryptophthalmos involving one eye. We report a three-stage reconstructive procedure in which a conchal cartilage 'sandwich' graft was first placed between the skin flap and the globe, mucous membrane subsequently grafted onto the inner surface of the cartilage graft, and lid level adjusted as the third stage.

Blepharoplasty↗
PubMed1997

Pilot in vitro toxicity study of 5-ALA and Photofrin in microvascular endothelial cell cultures.

Complicated hemangiomas are unique problems in which intervention with the proper laser can be an ideal solution. In this study we evaluated the toxicity of 5-Aminolevulinic acid (5-ALA) and Photofrin using in vitro models. The in vitro toxicity of 5-ALA and Photofrin was examined in a microvascular endothelial cell (MEC) culture system. The measurement of the percentage of MEC killed by various drug concentration using fluorescence viability assay. MEC incubated with 5-ALA at various concentrations for evaluation of dark toxicity showed less than a 50% cell kill. A comparison of different intervals of subcultured MEC showed that the early subculture (3 days after primary culture) is more vulnerable than later subculture (7 days after). Cells treated with Photofrin at various concentrations exhibited less than 50% cell kill (dark toxicity). The comparison of different intervals of subculture (3 days and 7 days after primary culture) showed a result similar to that of 5-ALA. All controls showed 0% cell kill. In conclusion, both 5-ALA and Photofrin are capable of destroying human microvascular endothelial cells in vitro. Drug concentrations and the power density for photodynamic therapy should be considered and will be included in our subsequent studies.

Aminolevulinic Acid↗
PubMed1995

Periorbital soft-tissue and socket reconstruction.

Deformities of the periorbital soft tissue and socket after trauma or infection may involve the bony framework, orbital contents, and periorbital soft tissues, requiring careful evaluation. Soft-tissue reconstruction necessitates the appreciation of a three-dimensional defect. Structural reconstruction in conjunction with prosthetic replacement of the globe requires careful planning. Three cases illustrating problems and results after reconstructions are presented.

Adult↗
PubMed1993

Use of split anterior tibial muscle flap in treating avulsion injury of leg associated with tibia exposure.

Avulsion injury of the leg may result in exposure of the anterior surface of the tibia in addition to skin loss. This exposed bone should be covered by a soft tissue flap to facilitate healing and provide durability. The split anterior tibial muscle flap is ideal in this situation because of its adjacent location, reliability, and simplicity. A cadaveric study demonstrated rich intramuscle vascular anastomoses between the segmental branches from the anterior tibial artery that provide safety in partial transfer. The technique of split anterior tibial muscle flap was applied successfully in 4 patients with leg avulsion injury associated with tibial bone exposure. The cosmetic result was good and the function of the muscle was preserved.

Adult↗
PubMed1990

Jadassohn's nevus sebaceous of the head and face.

The nevus sebaceous is a congenital skin lesion that usually appears in the head and face area. The lesions often cause aesthetic problems for patients and have a high incidence of malignant degeneration. The nevus sebaceous is rarely discussed in plastic surgery literature, however. This article describes 62 cases with a review of the literature.

Adolescent↗
PubMed1990

Traumatic eyelid invagination: case reports.

Three rare cases of upper eyelid trauma are presented. In high-speed traffic accidents, the upper eyelids were penetrated by glass, avulsed, and then, together with pieces of glass, pushed over the globe and buried deeply in the retrobulbar area. The invaginated eyelids were pulled out gently, the conjunctiva still attached to the globes. They were repaired primarily. In these patients eyelid function and cosmesis were preserved.

Accidents, Traffic↗
PubMed1989

Complications of Oriental blepharoplasty.

The complications of Oriental blepharoplasty are described according to their clinical appearance and anatomic findings at the time of surgery. The surgical correction of these complications is presented. A total of 42 patients with complications following blepharoplasty were treated. The types of deformities were categorized from their external appearance as asymmetry, retraction and ectropion, blepharoptosis, supratarsal depression, fading of the lid fold, and hemorrhage. The causes of each type of complication are identified according to the intraoperative findings, and the correlation between preoperative and intraoperative findings is explained. Correction of these complications follows identified guidelines, and the results were good to satisfactory.

Adult↗
PubMedDate not supplied

Circumnipple-incision, longitudinal-breast dissection augmentation mammaplasty.

A modification of circumnipple breast augmentation is described, which confines the minimal scar to the base of the nipple. Furthermore, a longitudinal breast parenchyma dissection is performed for breast pocket dissection that limits the injury of the lactiferous ducts and nerves to a minimum, and makes dissection and exposure of the pocket easier, even in patients whose nipples are small. This technique is especially useful in small breasts. We have performed this procedure in 57 patients, and the few complications to date are discussed in this paper.

Breast Implantation↗