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Biomedical subjects

C J van Dam

Publications and source records attributed to C J van Dam.

4 recordsLinked to original sources

Syndromic approach to STD case management: where do we go from here?

In the absence of aetiological tests for the diagnosis of individual sexually transmitted diseases (STD), the syndromic approach has been developed as an effective and appropriate case management strategy. Algorithms provide guidance to healthcare workers and ensure standardised approaches to case management. The syndromic approach, utilising currently available algorithms, works well in the management of people with symptomatic urethritis, genital ulcer disease, and vaginitis. Owing to the frequently asymptomatic nature of gonococcal and/or chlamydial cervicitis, and the lack of specific defining risk factors and/or signs and symptoms, the syndromic approach performs less well in the identification and management of women with cervicitis. The syndromic approach can and should be adopted for the management of patients with urethral discharge, genital ulceration, vaginal discharge, and cervical signs. Further research is needed to improve the identification and management of cervical infections; to guide policy makers in selecting the most appropriate disease control strategy; to improve utilisation of available and future tests; to develop affordable, rapid, and simple diagnostic tests; and to develop STD vaccines.

Algorithms↗

The provision of safe blood--policy issues in the prevention of human immunodeficiency virus transmission.

The AIDS epidemic has focused attention on the constraints and deficiencies present in many blood transfusion services in the developing world. We discuss a variety of options for reducing transfusion-related HIV transmission, and suggest how new transfusion strategies may be implemented. We show that a transfusion service cannot rely solely on the screening of donor blood for anti-HIV antibodies and that a more comprehensive approach is needed. Important components of this approach include donor selection and improved clinical practice, in which blood and blood products are prescribed only when really necessary.

Biological Products↗