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Biomedical subjects

C Jürgens

Publications and source records attributed to C Jürgens.

10 recordsLinked to original sources

[Some references for Ilisarov transosseous osteosynthesis].

The advantages of secondary bone healing by callus formation--as seen in transosseous osteosynthesis--as against primary bone healing are discussed. With the Ilisarov technique, new callus and bone formation can be achieved under constant tension stress. Observations of the phenomenon of limb lengthening by callus distraction go back to Codivelli. A first apparatus for bone lengthening was described by Block as long ago as 1923. The tremendous merit of Ilisarov's work is based on fundamental research and clinical experience with investigation of the effects of tension stress on several sorts of tissue under different conditions.

Bone Lengthening

[Ilisarov ring fixation and its technical application].

The Ilisarov ring fixator is an extremely versatile external fixation device. There is a wide range of indications for its use, e.g. fractures, pseudarthroses and non-unions, large defects, deformities and limb shortening. The device consists of rings or half-rings, which are connected to each other by threaded rods or plates and to the bone by wires under tension. This design allows neutral fixation, compression or distraction of the bone fragments. Because of its low axial stiffness at low loads and increased stiffness at higher loads, this fixator promotes osteogenesis and reduces strain on the tissues in functional treatment. Surgical intervention for its application is minimally invasive. This is a useful addition to the orthopaedic surgeon's armamentarium, providing proper attention is paid to preoperative planning, the principle rules of frame design and wire insertion technique, and postoperative management.

Biomechanical Phenomena

[Treatment of post-traumatic limb shortening].

The physiological phenomenon of changes in callus formation during distraction was first described by Codivilla at the beginning of this century. Having investigated and proved the influence of tension stress on callus formation, Ilizarov used this as a method to treat limb shortening and deformities. Because of his remarkable results we introduced this method in our hospital in 1990, using the original Ilizarov ring fixator. From November 1990 to December 1991, we used this technique in 10 cases of combined post-traumatic bone shortening with deformity (the tibia was affected in six patients, the femur in three and the forearm in one). The mean shortening was 3.1 cm, the mean varus or valgus deformity 9.5 degrees, the mean anteflexion or recurvation 8.3 degrees, and the mean rotation deformity 8.5 degrees. Distraction/correction lasted between 8 and 55 days (mean: 37 days). Fixation was necessary for between 60 and 339 days. If corticotomy was performed in the diaphyseal bone, fixation lasted almost twice as long (11.33 days/mm lengthening) as in the metaphyseal area (6.55 days/mm lengthening). There were 14 complications, most of which were considered minor. The latter included pin infections (4), wire breaking (1) and restricted range of motion of the knee or ankle (5). Among the major complications were two nerve irritations, which recovered spontaneously, and two pin-induced local bone infections, which required surgical intervention. Achievement of the goals of treatment-complete correction of shortening and deformity-was not affected by these complications.

Adult

[Treatment of chronic joint malposition].

We report three cases of chronically dislocated joints of the lower extremities that were treated by the Ilisarov method. As the results show, it is possible to reduce such dislocations step by step, causing less operative trauma.

Adult

[Experience with uretero-neocystostomy in 338 kidney transplantations].

In 338 consecutive human kidney transplants since 1972 uretero-neocystostomy was performed in a typical manner. The technique is a modification of Leadbetter's ureterosigmoid anastomosis and it is used for all cases of ureteral reimplantation at our institution. The rate of operative complications belonging to the urinary tract is 4.8%. In 29% out of 31 reexamined patients a vesico-ureteral reflux to the transplant appeared. We believe that the demonstrated method is useful for reconstruction of the urinary tract in renal transplants.

Anastomosis, Surgical

[Interventional sonography after kidney transplantation].

In cases of urinary fistulae as well as lymphoceles the only ultrasound-guided percutaneous nephrostomy has led to a good result. In cases of ureterostenosis and distal fistulae the renal function could be preserved by percutaneous nephrostomy. The anterograde pyelography was exact in demonstrating localization of the stenosis which led to a better operative procedure. The interventional ultrasound therefore represents an important option in the treatment of operative complications after kidney transplantation.

Humans

[Development of a resorbable temporary skin replacement for large surface burn wounds].

Most of the temporary dressing used in the treatment of extensive burn wounds pose immunological permeability, or transparency problems. All available dressings must be removed, and removal is often painful and traumatic. The development of biodegradable wound dressings made of copolymers of lactic and caproic acid was part of a research program (BMFT/FRG). Four parameters determine the properties of the copolymers: Purity, mole ratio of monomers, molecular weight, and sequence. Films of these copolymers can be made transparent, permeable, and flexible. They are degraded by hydrolysis and the normal ways of metabolism.

Animals