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Biomedical subjects

C Jackson

Publications and source records attributed to C Jackson.

8 recordsLinked to original sources
PubMed1978

Subcellular localisation and identification of superoxide dismutase in the leaves of higher plants.

1. The subcellular location of superoxide dismutase in the leaves of spinach and other C3 plants has been investigated. 2. Most activity appeared to be located within chloroplasts. These organelles contain a cyanide-sensitive (copper-zinc) superoxide dismutase, most of which is located in the stroma although some is bound to the thylakoids. 3. Intact chloroplast fractions also contain a cyanide-insensitive (manganese) superoxide dismutase, but this activity is located on the outside of the chloroplasts and may be adsorbed onto them during isolation. 4. Leaf mitochondrial fractions contain only a small percentage of total leaf superoxide dismutase activity, but there is more than can be accounted for by contamination with chloroplasts. 5. Mitochondria contain both a cyanide-sensitive dismutase, apparently located in the intermembrane space, and a cyanide-insensitive activity, apparently located in the matrix. 6. The microsomal fraction contains no superoxide dismutase activity.

Chloroplasts↗
PubMed1978

The use of high speed gel filtration for the detection of rubella-specific IgM.

Three new gels, Ultrogels AcA 22, AcA 34 and AcA 44 have been compared with Sephadex G-200 for the detection of rubella-specific IgM. Ultrogel AcA 44 did not achieve an adequate separation of IgM and IgG. Ultrogels AcA 22 and AcA 34 gave clear separation of IgM and IgG but only the latter could be operated at flow rates significantly higher than Sephadex G-200. With rubella convalescent sera fractionation with Ultrogel AcA 34 leads to a 2-4-fold loss of sensitivity for the detection of the first peak of rubella HI activity which is associated with recent infection. This is largely due to the occurrence of specific IgA antibody in the first peak of rubella HI activity after Sephadex G-200 fractionation but not after Ultrogel AcA 34 fractionation.

Antibody Specificity↗
PubMed1975

Prophylactic ampicillin therapy for vaginal hysterectomy.

Ampicillin was given to a group of 41 patients undergoing vaginal hysterectomy with and without vaginal repairs. This group was compared with 106 patients who received no antibiotic therapy. Retrospective analysis revealed both groups were the same when compared for race, parity, socioeconomic status, blood loss, operator experience and phase of the menstrual cycle. There was significantly less morbidity, infection and serious infections in the antibiotic-treated group than in the control group. In addition, significantly fewer complications of any type, fewer courses of therapeutic antibiotics and fewer readmissions for postoperative complications were noted in the group receiving prophylactic antibiotics. It is suggested that any patient undergoing a procedure which invades the peritoneal cavity by operating through the vagina should be placed on prophylactic antibiotics.

Ampicillin↗