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C Jadot

Publications and source records attributed to C Jadot.

6 recordsLinked to original sources

Haemodialysis in schizophrenia: a double blind study - preliminary report.

The therapeutic effects of haemodialysis were evaluated in schizophrenic patients using a double blind procedure. Twelve patients were diagnosed as acute schizophrenics according to Feighner's criteria for psychopathology. After obtaining informed consent, the patients were randomly assigned to active haemodialysis (AD) or sham dialysis (SD). An 8 days "drug washout period" was followed by AD or SD treatment of 4 weeks (two 5 hours sessions per week) and psychopathological evaluations were performed regularly in a blind fashion using the Brief Psychiatry Rating Scale (BPRS) and the Comprehensive Psychopathological Rating Scale (CPRS). Nine of the 12 patients were improved by both extracorporeal procedures with or without active dialysis. No significant difference appeared however between both groups in the rate and degree of improvement of nuclear symptoms of schizophrenia. Nevertheless, AD was significantly more efficient in relieving affective symptomatology, suggesting the potential involvement of some endogenous dialysable substance (s) in the pathogenesis of mood disturbances in schizophrenia.

Adult↗

[Contribution of the electrophysiological study of sleep in psychiatry (author's transl)].

The authors briefly remind us of physiological characteristics of normal sleep and its modifications in psychiatric disorders. They draw attention to the numerous possibilities in the clinic of using electrophysiological sleep research. This is of importance in an area where few biological markers are available for the diagnosis and the treatment. Furthermore, sleep studies support the hypothesis of disturbances in circadian rhythms in affective disorders.

Affective Disorders, Psychotic↗

[Sleep disturbances. Toward a new classification (author's transl)].

Various epidemiological studies show that sleep disturbances are very frequent. The clinician often treats these disturbances in a non specific way with hypnotic medication. He by-passes the diagnostic steps by doing this. Recently our knowledge on normal and pathological sleep has much increased. The aim of this article is to show that it is now possible to define a rational diagnostic approach having therapeutic implications.

Alcoholism↗