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Biomedical subjects

C Jaeger

Publications and source records attributed to C Jaeger.

43 records · Page 3Linked to original sources

Measurement of ventilation during cardiopulmonary resuscitation.

Determining adequacy of mechanical ventilation is as important during CPR as in a more stable situation (such as, a patient on a ventilator in an ICU). Yet, such assessment during CPR usually only means listening for breath sounds, checking chest excursion, and blood gases. Exhaled tidal volume (VT) was measured on 45 intubated adult patients during resuscitation using a Wright's spirometer attached to a T-valve above the endotracheal tube. Ten patients had aspiration prior to intubation; 15 received advanced cardiac life support in the field, including esophageal airway insertion. CPR was performed in all cases with a mechanical compression device (Thumper). The pressure ventilator on this device was calibrated (peak inspiratory pressure, VT vs compliance) using a Dixie Test Lung, allowing indirect assessment of pulmonary compliance during CPR. Our findings suggest that lung compliance is markedly reduced within a short time after cardiac arrest. Fifty-five % of patients in this series could not be adequately oxygenated (PaO2 less than 50 torr) despite an FIO2 of 0.8 and adequate ventilation. Due to the reduced cardiac output during CPR causing venoarterial shunting, it is speculated that pulmonary edema is the most plausible explanation for this observation.

Aged↗

Follow-up of spontaneous intracerebral haemorrhage by computed tomography.

The follow-up of 89 patients with spontaneous intracerebral haematomas was studied by computed tomography (CT). The aetiology of the haemorrhage was found to be hypertension in 52 cases, vascular malformation in 14 cases, and two haematomas were due to anticoagulant therapy. The lesion visible on CT consisted of an area of increased density surrounded by a rim of low attenuation. Most cases showed a progressive decrease in size of the total lesion. Exceptions to this pattern were observed, which may lead to the misdiagnosis of a tumour. The central area of increased density decreased in size much more quickly than the total lesion. Signs of a mass effect were observed up to the ninth week in the larger lesions. The resorption of blood, measured by the decrease in diameter of the central high attenuation area, was not dependent on the site or original size of the haematoma, but was slower in hypertensive haemorrhage than in haemorrhage due to vascular malformation. Contrast enhancement was observed up to the ninth week and was ring-like in most cases. Our data confirm the well-known finding that the bleeding cannot be demonstrated by examination of the CSF if the blood has not reached the ventricular system or the subarachnoid space.

Adolescent↗

X-linked ocular albinism: a family containing a manifesting heterozygote, and an affected male married to a female with autosomal recessive ocular albinism.

A pedigree of X-linked ocular albinism is presented containing nine affected males and 10 heterozygous females. One carrier female showed ocular changes similar to those of affected males. She is considered to be a manifesting heterozygote, a situation explained by the Lyon hypothesis. One affected male married a female with autosomal recessive ocular albinism and produced one daughter with the fundus changes of the carrier state of X-linked ocular albinism, and one son with normal eyes. The daughter did not show any evidence of the additive effect of the two different genes for X-linked and autosomal recessive ocular albinism.

Albinism↗

The electronic clipboard: an automated system for accurately recording events during a cardiac arrest.

An electronic clipboard has been developed which is simple to used and allows for the accurate timing and recording of events during a cardiac arrest. A flowsheet made of translucent 8 1/2 inches by 11 inches paper is clipped to a plastic board. Along the left margin of the flowsheet is a list of common events and therapies which should be recorded during a cardiac arrest (ie, cardiac rhythm, defibrillation, intubation, intravenous (IV) therapy, medications, etc). Across the page next to each category are columns of boxes, illuminated from below automatically by bars of light from the clipboard at one-minute intervals. Comparison of the events recorded during the first 20 minutes of cardiac resuscitatioon in an emergency department in 18 patients using the electronic clipboard method versus 18 randomly selected, matched patients with conventional recording methods demonstrated the superiority of the newer technique. More total events were recorded with the electronic clipboard (P less than 0.005), especially in the following categories: use of cardiopulmonary resuscitation Thumper, cardiac rhythm, defibrillation, sampling of arterial blood gases, IV insertion, and use of medications. The flowsheet is a superb instrument for reconstructing events for scientific analysis, legal documentation, and education.

Electric Countershock↗