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Biomedical subjects

C Jean-Girard

Publications and source records attributed to C Jean-Girard.

6 recordsLinked to original sources

[Tolerance of famotidine. Study of network of sentinel physicians in pharmaco-vigilance].

This paper presents the results of an intensive surveillance based on a network of general practitioners and following 200 patients treated by famotidine 40 mg per day during 6 to 8 weeks. Four patients with a previous experience of adverse reaction to another H2 antagonist did not relapse with famotidine. None interaction was reported with drugs such as beta-blockers, oral anticoagulants, theophylline, benzodiazepines, calcium antagonists. Twenty four clinical side effects were reported; For 5 patients (2.5%) the treatment had to be stopped. The most common side effects were neurological. The results are compared with those of previously published studies.

Adult↗

[Prospective OMEGA survey (Drug use-pregnancy relationship survey at the French Riviera)].

The survey of drugs used during pregnancy is necessary and the need for prospective studies is recognized. Health book distribution where drug intake is written since the beginning of the pregnancy allows a narrow therapeutic survey. The 350 first books analysis show that pregnant women use an average of well resorbed 1.8 drugs during 1rst and 3rd pregnancy trimesters. The most commonly used drugs are vitamins and iron (by 56% of women), non-narcotic analgesics (40%), antibiotics (40%), veinotonics (38%) and hormonal treatments (25%).

Abnormalities, Drug-Induced↗

[[Multilocular solitary renal cyst. 2 adult case reports with review of the literature].

The authors report 2 cases of renal multilocular cyst and review 250 cases reported in the literature, revealing the original features of this benign tumour which has an equal incidence in children and adults with a controversial acquired or malformative aetiopathogenesis, precise histological features, but a difficult preoperative and intraoperative diagnosis despite modern imaging techniques. In the great majority of cases, treatment consists of nephrectomy.

Adult↗