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Biomedical subjects

C Jenni

Publications and source records attributed to C Jenni.

8 recordsLinked to original sources

[Human bone marrow burden in dermatologic radiation].

The exposure to radiation of the entire red bone marrow was determined in three dermatologic X-ray treatment situations by means of a phantom in which the bones were supplied with 55 measuring sites. In each measurement the field was in the area of the left cheek. The parameters of radiation were in measurement 1/2/3: voltage = 50/43/43 kV, filter = 1.0/0.6/0.6 mm Al, field = 12.5/12.5/3.0 cm diameter, focus-skin distance = 30/30/15 cm, tissue half-value thickness = 13.0/7.5/5 mm. Related to a surface dose of 400 rad, the radiation exposure of the red marrow was 1555 mrad in measurement 1, 556 mrad in measurement 2 and 118 mrad in measurement 3. These results are discussed. The exposure to radiation of the red marrow in dermatologic X-ray treatments is not negligible and should not be omitted when evaluating the benefit and risk of dermatologic X-ray treatments.

Bone Marrow↗

[Syphilis, infection and serology].

The in- and out patient departments of Dermatology report in Switzerland every year between 300 to 400 newly diagnosed cases of syphilis--mostly primary syphilis--to the federal public health service. The serological tests decisive for such a diagnosis have been fundamentally changed in the last few years. Among the classical tests only the cardiolipin complement binding test (Card-CFT) and the VDRL test remain still valuable. They are suitable for controlling the course of disease after treatment. Nowadays two tests are essential for the diagnosis, i.e. the TPHA and the FTA-ABS. They are highly specific for syphilis and become already positive between the 2nd and the 3rd week after inoculation. On the other hand these tests are of no value for the follow-up after therapy. A positive FTA-ABS-19S-IgM test indicates the necessity of treatment. Practical examples may illustrate the interpretation of different reactions.

Adult↗

[Eczema of the lower leg--clinical, allergological and differential diagnostic aspects].

More than 50% of patients with dermatitis of the lower legs have a contact allergy. In 60 of our out-patients, the most frequent allergens were found to be balsam of Peru, lanolin and terpentine, followed by benzocaine, p-phenylenediamine, neomycin, oxychinoline, and parabens. Contact sensitization should be chiefly suspected in patients showing resistance to treatment despite apparently adequate therapy, and in those complaining of intolerance to definite topical treatment. Further indices are vesiculation and oozing in the environment of the ulceration, or scattered foci of dermatitis in the face (blepharoedema) or on the hands. The importance of patch testing is emphasized. Suggestions for differential diagnosis and treatment are given.

Allergens↗

[Carcinoma erysipelatodes (author's transl)].

Carcinoma erysipelatodes (inflammatory metastatic carcinoma) is a rare metastatic carcinoma in the skin. It is usually associated with breast carcinoma, and the prognosis is short-termed. It closely resembles an acute infection, such as erysipelas or cellulitis. 2 patients with this syndrome are presented. One of them had carcinoma of portio uteri. The clinical appearance and the histological pathognomony are described, and a review of the literature is given.

Breast Neoplasms↗

[Diagnostic problems associated with the coincidence of bullous dermatosis and lupus erythematosus visceralis. Demonstration of a case with Duhring's dermatitis herpetiformis in association with visceral lupus erythematosus].

This report describes a patient, whom we observed for 3 years, exhibiting a coincidence of dermatitis herpetiformis Duhring and systemic Lupus erythematosus. The difficulties involved in demarcating bullous lupus erythematosus from the more rare association of bullous pemphigoid or dermatitis herpetiformis with systemic lupus erythematosus are discussed in connection with differential, histological, direct and indirect immunofluorescence diagnostic aids.

Adult↗