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Biomedical subjects

C Jezyna

Publications and source records attributed to C Jezyna.

At least 19 recordsLinked to original sources
PubMed1989

[Clinical problems of staphylococcal septicemia].

Clinical Problems in staphylococcal septicaemia are reported in the observed 13 cases with severe multiorgan complications. In 69.2% of patients the course of the disease was very serious or severe, in the remaining cases it was moderately severe. Attention is called to the variety of clinical patterns and to frequent involvement of the central nervous system, cardiovascular system and respiratory system during septicaemia. The therapeutic management included, besides combined treatment with three antibiotics of synergistic action, antistaphylococcal serum, glucocorticoids, agents increasing the general resistance of the organism (transfusion of fresh blood, gamma-vein, gammaglobulin), cardiac drugs and symptomatic drugs, and in some cases cytochrome and heparin. Particular attention was given to adequate nursing care. Two patients died (15.4%).

Adolescent↗
PubMed1989

[Suppurative meningitis in 210 cases].

Clinical course, etiology and the results of treatment of the suppurative meningitis in 219 adult patients are discussed. Clinical course was extremely severe in 63.3% of the patients, moderately severe in 33.8% of the patients, and complicated by various coexisting disorders and skull trauma in several patients (35.7%). Mortality rate was 8.6%. Combined therapy with 2 or 3 synergetically acting antibiotics was administered. An emphasis is on diagnostic problems especially in patients treated with various antibiotics prior to hospitalization (37.1%) and low percentage of bacteriological tests (22.9%).

Adolescent↗
PubMed1986

Liver histology in chronic metribuzin poisoning of the guinea-pig.

Forty male guinea-pigs weighing 400-600 g, 8 months old, were given metribuzin directly into the gastric lumen over a period of 30 days (20 animals) or 90 days (20 animals), 6 times a week. The intoxicated animals showed congestion and obliteration of the trabecular structure of the liver. Acidophilic and vacuolar degeneration of the liver cells with signs of necrosis were also observed. Histochemical tests revealed a poorer staining for glycogen and succinic dehydrogenase and intensification of the alkaline and acid phosphatases reaction. The above findings indicate a progressive degeneration due to metribuzin of different organelles of the liver cells including nuclei, mitochondria, lysosomes, microvilli and the cytoplasm.

Animals↗
PubMed1985

Carbohydrate, protein and glycoprotein metabolism by the guinea-pig liver in chronic metribuzin poisoning.

Male guinea-pigs weighing 400-600 g, 8 months old, were given metribuzin directly into the gastric lumen over a period of 30 days (20 animals) or 90 days (20 animals) 6 times a week. In the liver of the poisoned animals, the glycogen level and the AspAT and AlAT activities, while in the serum the total protein and the fractions albumin, alpha 1-globulin and gamma-globulin significantly decreased; serum glucose and the serum fractions alpha 2-globulin and beta-globulin, each showed an increase. The glycogen level in the liver, total protein, glucose as well as the alpha 1 and alpha 2 globulin fractions in the serum showed not appreciable difference between 30 and 90 days of intoxication. After 90 days of metribuzin treatment AspAT and AlAT dropped in the liver and rose in the serum, in comparison to the 30-day values. As to the parameters of glycoprotein metabolism, the intoxicated animals showed a significant decrease and increase in concentration of hexosamines and sialic acids in the liver and serum, respectively. Metribuzin intoxication also cause a significant decrease in activity of glucosamine phosphate isomerase and significant increase in activity of glycosidases in the liver. The results suggest that metribuzin disturbs the metabolism of carbohydrates, proteins and glycoproteins in the guinea-pig liver.

Aldose-Ketose Isomerases↗
PubMed1984

[Epidemiologic and clinical studies of patients with tick-borne encephalitis from northeastern Poland].

The authors discussed the epidemiological and serological evaluation as well as the clinical symptomatology of thick-borne encephalitis in 215 patients from North-East Poland. They found, among other things, that in 94 per cent of cases the infection was percutaneous from the tick bite and caused via the digestive route in 6 per cent of cases by drinking unboiled cow milk. It was demonstrated that during the late phase of convalescence i.e. one to five years after the outbreak of the disease, the injuries to the nervous system were more frequently manifest than in patients during the acute phase. The authors pointed out that 25.3 per cent of those who recovered from tick-borne encephalitis, suffered to a varying degree from a limited physical and psychic efficiency. This condition originated from the existing injuries to the nervous system and led not infrequently to a permanent disability of the persons concerned.

Adolescent↗
PubMed1983

[Chronic toxoplasmosis in pregnant women--an epidemiological and social problem].

Frequency of pregnancy miscarriage was analized in 52 women with chronic toxoplasmosis treated clinically. The pregnancy miscarriage was found in 78.4% of cases including abortion-48.7%, premature and immature delivery resulting in death-17.1% and newborns with congenital defects-12.6%, of with 78.6% died shortly after the delivery. The percentage of normal pregnancy amounted to 21.6% and in 3 cases newborns with congenital defects survived. It was shown that chronic toxoplasmosis is dangerous for successive pregnancies and it is not restricted to one pregnancy only.

Abortion, Spontaneous↗