PubMed Health⌕ Search

Biomedical subjects

C K Campbell

Publications and source records attributed to C K Campbell.

At least 19 recordsLinked to original sources
PubMed1995

Hazards to laboratory staff posed by fungal pathogens.

There is sufficient evidence from the literature to demonstrate the risk involved in handling the dimorphic pathogens without suitable containment facilities. The number of fungi considered a severe hazard is fortunately low, but impeccable working practices and continuous vigilance are necessary to minimize accidents and to prevent them leading to worse catastrophies. The continuing discovery of new opportunistic pathogenic fungi requires frequent, objective and cautious review of the hazard groupings to accommodate them.

Fungi↗
PubMed1995

Evaluation of the AUXACOLOR system, a new method of clinical yeast identification.

AIMS: To compare the AUXACOLOR yeast identification system with the API 20C system. METHODS: Yeast isolates (n = 215), comprising 16 species, were identified using the AUXACOLOR system and the API 20C system. Isolates that could not be identified with the API 20C system or which produced discrepant results in the two systems were identified by assimilation and fermentation procedures. RESULTS: AUXACOLOR correctly identified 150 (85.7%) of 175 germ tube negative isolates while API 20C identified 155 (88.6%). Incorrect identifications were more common with API 20C (7.4%) than with AUXACOLOR (3.7%). Of 110 isolates of four common pathogens (Candida glabrata, C parapsilosis, C tropicalis, and Cryptococcus neoformans), 82.7% (91/110) were identified by AUXACOLOR while API 20C identified 74.5% (82/110). Of 65 less common germ tube negative isolates, 55.4% (36/65) were identified by AUXACOLOR while API 20C identified 63.1% (41/65). CONCLUSION: Although it has a limited database of 26 species, the AUXACOLOR system is a useful method for identification of germ tube negative clinical yeast isolates. Compared with the API 20C, the AUXACOLOR system is simpler and quicker to set up, easier to interpret, and comparable in cost.

Candida↗
PubMed1994

Successful treatment of sinusitis caused by Cunninghamella bertholletiae.

Seventeen cases of infections due to Cunninghamella species have been reported worldwide in humans, and there have been only three survivors. We report a case of paranasal sinusitis due to Cunninghamella bertholletiae in an elderly patient who had diabetes mellitus and myelodysplasia. After receiving 7 weeks of therapy with deoxycholate amphotericin B (44 mg/kg or a total of 3 g) and rifampin, the patient was cured and did not have to undergo radical surgery.

Aged↗
PubMed1990

Pythiosis.

Explore the source record for details and available documents.

Animals↗
PubMed1989

Mycology quality assessment: United Kingdom national scheme.

A mycology quality assessment scheme introduced in 1986 was assessed: 289 laboratories participated in the scheme, and six distributions, each containing four specimens, were made. Levels of performance varied considerably among participating laboratories: performance was highest with the commoner organisms distributed, but some laboratories, encouragingly, achieved a consistently high level of species identification. A questionnaire distributed to participants showed that a wide range of methods are commonly used, some of which are contrary to good practice. As the scheme continues, selection of organisms considered to be relevant and of use to participants will become difficult.

Arthrodermataceae↗
PubMed1989

Isolation of dysgonic strains of Microsporum canis in Bilbao (Spain).

In this report, we describe five cases of dermatophytosis caused by dysgonic strains of Microsporum canis which occurred in the area of Bilbao (Spain). The clinical presentations and responses to treatment of these infections were apparently similar to those caused by typical strains of this species but the increasing prevalence of dysgonic and other atypical strains of M. canis and the relative stability of the dysgonic morphology are the important features shown in our study. Contact with animals was confirmed by all of the patients, but in only one case was this possible infectious origin demonstrated mycologically. One of the patients, a heroin abuser with AIDS, showed a simultaneous infection with Trichophyton mentagrophytes var. mentagrophytes.

Adult↗
PubMed1987

Polycytella hominis gen. et sp. nov., a cause of human pale grain mycetoma.

A hyphomycete isolated from a pale-grain eumycetoma in an indian male patient is described as a species of a new form-genus, Polycytella hominis. The fungus is characterized by elongate multiseptate conidia in which only the apical compartment becomes thick-walled and retains viable cytoplasm. The appearance of P. hominis in the host tissues is described and compared with other pale-grain eumycetomas.

Adult↗
PubMed1986

Conidiogenesis of fungi pathogenic for man.

Despite an apparent stabilizing of nomenclature and concepts involved in fungal conidiogenesis during the past decade, there is now evidence that a much more complex and demanding approach to the descriptive study of processes involved in conidial formation would allow a more phylogenetically realistic classification of anamorphic fungi. The present review attempts to evaluate data on the human pathogenic molds in light of this new approach and to relate conidiogenesis to the known teleomorph connections of the fungi concerned. It is hoped that by treating the species in groups corresponding to their sexual affinities, it may be possible to infer homologous forms of conidiogenesis by comparative morphology and development.

Arthrodermataceae↗
PubMed1983

Disseminated zygomycosis (mucormycosis) caused by Saksenaea vasiformis.

A 14-year-old child from Iraq presented with an acute febrile illness accompanied by large necrotic skin lesions and bronchopneumonia from which he subsequently died. The infection was caused by an unusual zygomycete fungus Saksenaea vasiformis. Previous reports of infection with this organism are rare and tissue invasion has usually followed traumatic injury. In the child reported here no predisposing abnormalities were apparent.

Adolescent↗
PubMed1983

A comparative study of dermatophytosis in coal miners and dermatological outpatients.

The causative organisms and susceptibility factors were compared in two groups of individuals with tinea pedis, coal miners (234) and dermatological outpatients (244). Trichophyton rubrum was the commonest dermatophyte in both groups, being isolated from 71% of infected miners and 77% of infected outpatients. The incidence of atopy in the outpatients, but not the miners, was significantly higher in individuals with T rubrum infections than in control groups. An analysis of the data from both groups suggests that in the coal miners, in whom there is a high risk of endemic dermatophytosis, susceptibility factors such as atopy are of less importance than in patients seen in a dermatological outpatient clinic in whom the risk of exposure to other sources of dermatophytosis is low.

Adolescent↗
PubMed1982

Conidiogenesis in Petriellidium boydii (Pseudallescheria boydii). A light and electron microscope study.

Slide cultures of the type strain of P. boydii Shear, showed percurrent production of conidia by light microscopy over a period of several hours. Scanning and transmission electron microscopy were used to examine the conidiogenesis. The conidiogenous cells developed annular ridges rather than typical annellophoric scars. Evidence that these ridges represented sequential spore production was shown by T.E.M. in the form of a discontinuity of the outer conidiophore wall at the widest point of each ridge.

Ascomycota↗