Biomedical subjects
C Kagan
Publications and source records attributed to C Kagan.
Effect of acyclovir, bromovinyldeoxyuridine, vidarabine, and L-lysine on latent ganglionic herpes simplex virus in vitro.
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Environments. 2. Private thoughts.
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Environments 1: Scenes of improvement.
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Percutaneous biopsy following positive bone scans.
When a bone scan reveals an abnormal radionuclide accumulation and the cause is uncertain, bone biopsy is sometimes necessary. One hundred thirty biopsies have been performed in our institution with a percutaneous needle guided by fluoroscopy. This procedure is safe and effective.
A multicentered study of lysine therapy in Herpes simplex infection.
Lysine appears to suppress the clinical manifestations of herpesvirus infection. 45 patients with frequently recurring herpes infection were given 312-1,200 mg of lysine daily in single or multiple doses. The clinical results demonstrated a beneficial effect from supplementary lysine in accelerating recovery from herpes simplex infection and suppressing recurrence. Tissue culture studies have demonstrated an enhancing effect on viral replication when the amino acid ratio of arginine to lysine favors arginine. The opposite, preponderance of lysine to arginine, suppresses viral replication and inhibits cytopathogenicity of herpes simplex virus. The codons characterizing herpes simplex DNA apparently specify production of viral capsids at the expense of host cell histones.
Radiographic changes in the posterior-superior iliac crests following bone marrow aspiration.
The appearance of multiple lucencies in the posterior-superior iliac crests of patients in a bone marrow transplantation program is described. These benign lucencies should not be misinterpreted as bone destruction in patients with malignant disease who undergo multiple bone marrow aspirations.
Letter: Lysine therapy for herpes simplex.
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