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C Kawada

Publications and source records attributed to C Kawada.

5 recordsLinked to original sources
PubMed1990

Trisomy 12 mosaicism in phenotypically normal fetuses following prenatal detection.

We report three cases of amniocentesis in which mosaicism for trisomy 12 was detected in two or more independent cultures. The parents elected to terminate the pregnancy in all three cases. Follow-up studies in two of the cases confirmed the mosaicism in fetal tissues (in subcutaneous tissue in one case; in fetal lung in the other), but not in blood. No fetal anomalies were evident by ultrasound or at autopsy. These results along with other reported cases demonstrate the difficulty in counselling for mosaic trisomy 12.

Adult↗
PubMed1988

The prenatal sonographic diagnosis of lethal multiple pterygium syndrome: a heritable cause of recurrent abortion.

Presumably, a large number of recurrent abortions are caused by lethal recessive syndromes whose diagnosis depends either on a known family history or on the identification of characteristic fetal phenotypic features on pathologic examination. Because these conditions are rare, family histories are seldom helpful, and nondirected postmortem examinations on degenerating samples are seldom enlightening. Serial ultrasonography beginning early in pregnancy may provide important information in the evaluation of recurrent abortion caused by lethal recessive disorders. Reported is the accurate prenatal sonographic diagnosis of lethal multiple pterygium syndrome in a patient with a history of recurrent abortions. This syndrome is characterized by multiple limb contractures with pterygia, facial clefting, intracranial abnormalities, cystic hygroma, progressive fetal edema, and fetal death by midgestation. Inheritance may be X-linked recessive. Lethal multiple pterygium syndrome should be considered in patients with a history of recurrent midtrimester losses.

Abnormalities, Multiple↗
PubMed1981

Triplet pregnancies.

Fifteen triplet gestations delivered over 23 years beginning with 1954 are reviewed. The mortality rate was 7.1% in the gestation period of 28 weeks or more. This mortality rate compares favorably with the 15% to 50% rate reported in the literature. Among the third babies of each set, there was a mortality rate of 14.3%, again confirming the high mortality rate reported in the literature. Morbidity in triplet gestations was equally elevated. Although the data do not suggest what the best method of delivery is, the increased morbidity and mortality for the third baby of the set delivered vaginally implies that a more liberal use of cesarean section may reduce the potential risks for that baby. Also, among the eight cesarean sections performed in pregnancies at 28 weeks of gestation or more that have been reported in the literature, none of the babies died during the neonatal period.

Apgar Score↗