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C Kayser-Gatchalian

Publications and source records attributed to C Kayser-Gatchalian.

5 recordsLinked to original sources
PubMed1976

Neuropsychiatric symptomatology with chronic renal insufficiency in the stage of compensated and decompensated retention. I. CNS disturbances.

80 strictly selected patients with chronic renal insufficiency with plasma creatinine values of 1.4--14.5 mg% were examined according to a fixed scheme to determine the presence of symptoms and signs of renal encephalopathy. The general cerebral symptoms complained of were headache in 33.4% of the patient material, dizziness in 30.3%, easy fatigability in 62.5%, giddiness in 18.8% and insomnia in 37.5%. The most prominent neurological findings were hyperactive deep reflexes in 30% and action tremor in 23.8%. The symptoms of organic brain syndrome were impairment of memory in 32.5%, weakness of concentration in 28.8% and lability of affect in 63.7%. Diffuse EEG abnormalities were found in 26.2%. While the clinical neuropsychiatric symptoms did not show any statistically significant correlation with the various internal medical data, a trend was observed in the greater number of pathological EEGs with an increase in the impairment of renal function. Furthermore, there was a statistically significant correlation, (alpha less than or equal to0.015) between the occurrence of pathological EEGs and the plasma creatinine and BUN values. It is remarkable that the patients with abnormal EEGs had a relatively low mean creatinine level of 5.89 mg%. The strict dietetic management of the patients is regarded as one of the deciding factors for the relatively low frequency of neuropsychiatric symptoms in the material studied.

Adult↗
PubMed1976

Neuropsychiatric symptomatology with chronic renal insufficiency in the stage of compensated and decompensated retention. II. Peripheral nerve disturbances.

80 strictly selected patients with chronic renal insufficiency with plasma creatinine values of 1.4-14.5 mg% were examined for clinical and electrophysiological signs of nephrogenic polyneuropathy. The motor symptoms complained of were cramps in 43.8% of the patients, "restless leggs" in 18.7%, muscular twitchings in 12.5%. It was emphasized that the first two symptoms do not always indicate the presence of polyneuropathy. 30% complained of paresthesias, 5% of "burning feet". The most frequent clinical finding was the impairment of vibration sense in the feet in 37.5% followed by diminshed appreciation of passive movement of the toes in 30%, weakening or absence of the ankle jerk in 23.8% and finally, weakening of the patellar reflex in 5%...

Adult↗
PubMed1976

[The EEG in chronic renal insufficiency (author's transl)].

In a strictly selected material of 80 patients, who were all outpatients of a special nephrological clinic, with chronic renal insufficiency with retention values of 1.4-14.5 mg% serum creatinine, an EEG was done besides thorough neurological and internal examinations. In 21 cases (26.2%) a pathological EEG in the form of background slowing and general dysrhythmia. There was a tendency to increase in pathological EEG findings in correlation with increase of the retention values. The patients with pathological EEG had on the average a creatinine value of 5.89 mg%, those without EEG findings had an average creatinine value of 3.98 mg%. The difference is statistically significant (alpha less than or equal to 0.015). It is notable that there is a statistical correlation (alpha less than or equal to 0.005) between the presence of pathological EEG and the motor conduction velocity of the peroneal nerve: only 12% of the patients with a conduction velocity of less than 43 m/sec had a pathological EEG while 60% of the patients with a conduction velocity of more than 43 m/sec had EEG findings. No statistical correlation were found between the EEG changes and other neurological and internal signs and symptoms, including cardiovascular findings like the blood pressure.

Adult↗